Evidence map›Paper›PMID 33326313›Full record

ReviewAmerican journal of physiology. Cell physiology2021

The H

Amity F Eaton, Maria Merkulova, Dennis Brown

Open access · hybridAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 152 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Direct energy consumption by inhibitory GABAFrontiers in neuroscience · 2026
    Article
  11. NaFrontiers in chemistry · 2026
    Article
  12. Article
  13. Lysosome as a Chemical Reactor.International journal of molecular sciences · 2025
    Review
  14. Article
  15. V-ATPase assembly at leaky lysosomes.Nature structural & molecular biology · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amity F EatonProgram in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Maria MerkulovaProgram in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-4626-2877
Dennis BrownProgram in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Harvard University · US

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3M
TRAINING IN CELL STRUCTURE AND FUNCTION IN NEPHROLOGYT32DK007540 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, DENNIS, SOBERMAN, ROY · 1986 to 2021
$7.2M
Defining protein:protein interactions for the regulation of renal V-ATPase function: role in expression, assembly and trafficking.R01DK121848 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, DENNIS · 2019 to 2023
$2.7M
NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK121848NIDDK NIH HHS T32 DK007540Office of Extramural Research, National Institutes of Health (OER) DK121848
6 · The paper itself

Abstract

A primary function of the H

Indexed as

SARS-CoV-2Angiotensin-Converting Enzyme 2COVID-19HumansProton-Translocating ATPasesSignal TransductionVirus InternalizationAngiotensin-Converting Enzyme 2Proton-Translocating ATPasesacidificationendosomal traffickingpathophysiologypH regulationproton pumping ATPase

Identifiers

PMID33326313
PMCPMC8294626
OpenAlexW3110996865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.