Evidence map›Paper›PMID 33326305›Full record

ArticleJournal of neurophysiology2021

Nicotinic receptor modulation of primary afferent excitability with selective regulation of Aδ-mediated spinal actions.

Jacob Shreckengost, Mallika Halder, Elvia Mena-Avila, David Leonardo Garcia-Ramirez, Jorge Quevedo, Shawn Hochman

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cholinergic Modulation of Locomotor Circuits in Vertebrates.International journal of molecular sciences · 2022
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jacob ShreckengostDepartment of Physiology, Emory University, Atlanta, Georgia.
Mallika HalderDepartment of Physiology, Emory University, Atlanta, Georgia.
Elvia Mena-AvilaDepartamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México City, México.
David Leonardo Garcia-RamirezDepartamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México City, México.
Jorge QuevedoDepartamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México City, México.
Shawn HochmanDepartment of Physiology, Emory University, Atlanta, Georgia.ORCID 0000-0001-6970-9067
Emory University · USInstituto Politécnico Nacional · MX

Funding

Control of sensory function in mammalian spinal cordR01NS065949 · NINDS · EMORY UNIVERSITY · PI HOCHMAN, SHAWN · 2010 to 2014
$1.9M
NINDS NIH HHS R01 NS065949
6 · The paper itself

Abstract

Somatosensory input strength can be modulated by primary afferent depolarization (PAD) generated predominantly via presynaptic GABA

Indexed as

Synaptic PotentialsAnimalsGanglia, SpinalMiceMice, Inbred BALB CNeurons, AfferentNicotinic AgonistsNicotinic AntagonistsRatsRats, Sprague-DawleyReceptors, NicotinicNicotinic AgonistsNicotinic AntagonistsReceptors, Nicotinicacetylcholinedorsal root potentialpresynaptic inhibitionprimary afferent depolarizationtubocurarine

Identifiers

PMID33326305
PMCPMC7948147
OpenAlexW3112054957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.