ArticleACS chemical neuroscience2021
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of
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Article in ACS chemical neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
What it found
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- GluN2D NMDA Receptors: Bridging Physiology and Pathology.Biological psychiatry · 2026Review
- Inhibition of GluN2B-containing N-methyl-D-aspartate receptors by radiprodil.Brain : a journal of neurology · 2026Article
- Enhancement of hippocampal interneuron excitability by NMDA receptor positive allosteric modulation.The Journal of physiology · 2025Article
- Quercetin alleviates neonatal hypoxic-ischaemic brain injury by rebalancing microglial M1/M2 polarization through silent information regulator 1/ high mobility group box-1 signalling.Inflammopharmacology · 2025Article
- Selective Cell-Surface Expression of Triheteromeric NMDA Receptors.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of theACS chemical neuroscience · 2023Article
- Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions.Cellular and molecular life sciences : CMLS · 2023Article
- Opportunities for Precision Treatment ofThe Journal of pharmacology and experimental therapeutics · 2022Article
- Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors.Frontiers in pharmacology · 2022Article
- Regulation of NMDA Receptor Signaling at Single Synapses by Human Anti-NMDA Receptor Antibodies.Frontiers in molecular neuroscience · 2022Article
- Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.Pharmacological reviews · 2021Review
- The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and CaMolecular pharmacology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 3 institutions in 2 countries.
Katie L StrongDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Matthew P EpplinDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.
Kevin K OgdenDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Pieter B BurgerDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.
Thomas M KaiserDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.
Timothy J WildingDepartment of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, United States.
Hiro KusumotoDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Chad R CampDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.ORCID 0000-0002-3415-4652
Gil ShaulskyDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Subhrajit BhattacharyaDepartment of Drug Discovery and Development, Auburn University, Auburn, Alabama 36849, United States.
Riley E PerszykDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
David S MenaldinoDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.
Miranda J McDanielDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Jing ZhangDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Phuong LeDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Tue G BankeDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.
Kasper B HansenDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.ORCID 0000-0002-3303-4819
James E HuettnerDepartment of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, United States.
Dennis C LiottaDepartment of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.ORCID 0000-0002-7736-7113
Stephen F TraynelisDepartment of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States.ORCID 0000-0002-3750-9615
Emory University · USWashington University in St. Louis · USAuburn University · US
Funding
Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP20GM103546 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2012 to 2021
$19.2MGlutamate receptors and human neurological diseaseR35NS111619 · NINDS · EMORY UNIVERSITY · PI Stephen F Traynelis · 2019 to 2026
$6.6MGLUTAMATE-GATED CHANNELS IN CENTRAL/PERIPHERAL NEURONSR01NS030888 · NINDS · WASHINGTON UNIVERSITY · PI HUETTNER, JAMES E · 1992 to 2016
$4.4MMechanism of Action of Novel Subunit-Selective NMDA Receptor ModulatorsR01NS065371 · NINDS · EMORY UNIVERSITY · PI TRAYNELIS, STEPHEN F · 2009 to 2018
$3.4MStructural and functional investigation of negative allosteric NMDA receptor modulationR01NS097536 · NINDS · UNIVERSITY OF MONTANA · PI Kasper Boe Hansen · 2016 to 2026
$3.4MLoss of Grin2a Promotes Hippocampal Hyperexcitability and Epileptiform ActivityF31NS113530 · NINDS · EMORY UNIVERSITY · PI CAMP, CHAD R. · 2020 to 2022
$135kNIGMS NIH HHS P20 GM103546NINDS NIH HHS F31 NS113530NINDS NIH HHS R01 NS030888NINDS NIH HHS R01 NS065371NINDS NIH HHS R01 NS097536NINDS NIH HHS R35 NS111619
Abstract
PubMed holds no abstract for this paper.
Indexed as
Receptors, N-Methyl-D-AspartateSynaptic TransmissionAllosteric RegulationModels, MolecularReceptors, N-Methyl-D-AspartateElectrophysiologyEPSCmolecular dynamicspositive allosteric modulator
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.