Evidence map›Paper›PMID 33325757›Full record

ArticleHuman vaccines & immunotherapeutics2021

Bactericidal antibodies against hypervirulent

Marzia Monica Giuliani, Alessia Biolchi, Pavitra Keshavan, Maria Moriondo, Sara Tomei, Laura Santini, Elena Mori, Alessandro Brozzi, Margherita Bodini, Francesco Nieddu and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Marzia Monica GiulianiPreclinical Evidence Generation, GSK, Siena, Italy.ORCID 0000-0002-6530-5951
Alessia BiolchiPreclinical Evidence Generation, GSK, Siena, Italy.
Pavitra KeshavanClinical Research and Development, GSK, Siena, Italy.
Maria MoriondoDepartment of Health Sciences, University of Florence and Meyer Children's University Hospital, Florence, Italy.ORCID 0000-0001-9653-8371
Sara TomeiPreclinical Evidence Generation, GSK, Siena, Italy.ORCID 0000-0002-5136-6876
Laura SantiniPreclinical Evidence Generation, GSK, Siena, Italy.ORCID 0000-0002-9638-7275
Elena MoriPreclinical Evidence Generation, GSK, Siena, Italy.ORCID 0000-0003-4697-9333
Alessandro BrozziData Science and Digital Innovation, GSK, Siena, Italy.
Margherita BodiniData Science and Digital Innovation, GSK, Siena, Italy.ORCID 0000-0002-7054-8712
Francesco NiedduDepartment of Health Sciences, University of Florence and Meyer Children's University Hospital, Florence, Italy.ORCID 0000-0003-4460-3631
Silvia RicciDepartment of Health Sciences, University of Florence and Meyer Children's University Hospital, Florence, Italy.
Thembile MzoloBiostat and Statistical Programming, GSK, Amsterdam, The Netherlands.
Marco CostantiniBiostat and Statistical Programming, GSK, Siena, Italy.ORCID 0000-0003-4709-2590
Chiara AzzariDepartment of Health Sciences, University of Florence and Meyer Children's University Hospital, Florence, Italy.ORCID 0000-0001-7236-1655
Michele PellegriniClinical Research and Development, GSK, Siena, Italy.ORCID 0000-0001-8505-9260
Evidence (Italy) · ITMeyer Children's Hospital · ILCentraal Bureau voor de Statistiek · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increase in invasive meningococcal disease (IMD) incidence was observed in Tuscany in 2015/2016, mainly due to hypervirulent clonal complex (cc) 11 strains. In a

Indexed as

Meningococcal InfectionsMeningococcal VaccinesNeisseria meningitidisAntibodies, BacterialHumansInfantVaccines, ConjugateAntibodies, BacterialMenACWYMeningococcal VaccinesVaccines, Conjugatecc11/cc334 clonal complexesHypervirulent MenC strainsMenACWY-CRM conjugate vaccineMenC-CRM conjugate vaccineoutbreak

Identifiers

PMID33325757
PMCPMC8078732
OpenAlexW3111626415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.