Evidence map›Paper›PMID 33325582›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2021

Conversion of left atrial volume to diameter for automated estimation of sudden cardiac death risk in hypertrophic cardiomyopathy.

Huzefa Bhopalwala, Nakeya Dewaswala, Sijia Liu, Christopher G Scott, James M Welper, Oluwatoyin Akinnusotu, Johan Martijn Bos, Steve R Ommen, Michael J Ackerman, Patricia A Pellikka and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Echocardiography (Mount Kisco, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Huzefa BhopalwalaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Nakeya DewaswalaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Sijia LiuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Christopher G ScottDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
James M WelperDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Oluwatoyin AkinnusotuDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Johan Martijn BosDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Steve R OmmenDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Michael J AckermanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Patricia A PellikkaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Jeffrey B GeskeDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Peter NoseworthyDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Adelaide M Arruda-OlsonDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-9541-9899
Mayo Clinic in Arizona · USMayo Clinic in Florida · USMayo Clinic · US

Funding

Novel Informatics Approaches for Ascertainment of PAD Status and Adverse OutcomesK01HL124045 · NHLBI · MAYO CLINIC ROCHESTER · PI ARRUDA-OLSON, ADELAIDE MARIA MARTINS · 2015 to 2019
$820k
NHLBI NIH HHS K01 HL124045
6 · The paper itself

Abstract

backgroundA subset of patients with hypertrophic cardiomyopathy (HCM) is at high risk of sudden cardiac death (SCD). Practice guidelines endorse use of a risk calculator, which requires entry of left atrial (LA) diameter. However, American Society of Echocardiography (ASE) guidelines recommend the use of LA volume index (LAVI) for routine quantification of LA size. The aims of this study were to (a) develop a model to estimate LA diameter from LAVI and (b) evaluate whether substitution of measured LA diameter by estimated LA diameter derived from LAVI reclassifies HCM-SCD risk.

methodsThe study cohort was comprised of 500 randomly selected HCM patients who underwent transthoracic echocardiography (TTE). LA diameter and LAVI were measured offline using digital clips from TTE. Linear regression models were developed to estimate LA diameter from LAVI. A European Society of Cardiology endorsed equation estimated SCD risk, which was measured using LA diameter and estimated LA diameter derived from LAVI.

resultsThe mean LAVI was 48.5 ± 18.8 mL/m

conclusionsSubstitution of measured LA diameter by estimated LA diameter in the HCM-SCD calculator did not reclassify risk.

Indexed as

Cardiomyopathy, HypertrophicDeath, Sudden, CardiacEchocardiographyHeart AtriaHumansRisk Factorshypertrophic cardiomyopathyleft atrial diameterleft atrial volume indexsudden cardiac death risk

Identifiers

PMID33325582
PMCPMC7986336
OpenAlexW3113360231

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.