Evidence map›Paper›PMID 33325368›Full record

ArticleeLife2020

Multi-contrast anatomical subcortical structures parcellation.

Pierre-Louis Bazin, Anneke Alkemade, Martijn J Mulder, Amanda G Henry, Birte U Forstmann

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Multiscale characterization of the human claustrum from histology to MRI.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Joint models reveal human subcortical underpinnings of choice and learning behavior.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. High-resolution quantitative TImaging neuroscience (Cambridge, Mass.) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Echoes from Intrinsic Connectivity Networks in the Subcortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  17. Review
  18. Neuroimaging at 7 Tesla: a pictorial narrative review.Quantitative imaging in medicine and surgery · 2022
    Review
  19. Article
  20. Whole-Brain Network Models: From Physics to Bedside.Frontiers in computational neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pierre-Louis BazinIntegrative Model-based Cognitive Neuroscience research unit, University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-0141-5510
Anneke AlkemadeIntegrative Model-based Cognitive Neuroscience research unit, University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-3234-353X
Martijn J MulderIntegrative Model-based Cognitive Neuroscience research unit, University of Amsterdam, Amsterdam, Netherlands.
Amanda G HenryFaculty of Archaeology, Leiden University, Leiden, Netherlands.ORCID 0000-0002-2923-4199
Birte U ForstmannIntegrative Model-based Cognitive Neuroscience research unit, University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-1005-1675

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

The human subcortex is comprised of more than 450 individual nuclei which lie deep in the brain. Due to their small size and close proximity, up until now only 7% have been depicted in standard MRI atlases. Thus, the human subcortex can largely be considered as terra incognita. Here, we present a new open-source parcellation algorithm to automatically map the subcortex. The new algorithm has been tested on 17 prominent subcortical structures based on a large quantitative MRI dataset at 7 Tesla. It has been carefully validated against expert human raters and previous methods, and can easily be extended to other subcortical structures and applied to any quantitative MRI dataset. In sum, we hope this novel parcellation algorithm will facilitate functional and structural neuroimaging research into small subcortical nuclei and help to chart terra incognita.

Indexed as

AdolescentAdultAge FactorsAlgorithmsAutomationBrainBrain MappingDatasets as TopicFemaleHumansMagnetic Resonance ImagingMaleNeuroimagingYoung Adultanatomical parcellationhumanneurosciencequantitative MRIsubcortex

Identifiers

PMID33325368
PMCPMC7771958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.