Evidence map›Paper›PMID 33324963›Full record

ArticleTranslational animal science2020

Evaluation of the pharmacokinetics and efficacy of transdermal flunixin for pain mitigation following castration in goats.

Meggan T Graves, Liesel Schneider, Sherry Cox, Marc Caldwell, Peter Krawczel, Amanda Lee, Andrea Lear

Open access · goldAbstract read
In one paragraph

Article in Translational animal science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Efficacy of transdermal flunixin in mitigating castration pain in piglets.Frontiers in pain research (Lausanne, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Meggan T GravesLarge Animal Clinical Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, TN.ORCID 0000-0002-2559-4402
Liesel SchneiderDepartment of Animal Science, University of Tennessee Institute of Agriculture, Knoxville, TN.
Sherry CoxBiomedical and Diagnostic Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, TN.
Marc CaldwellLarge Animal Clinical Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, TN.
Peter KrawczelDepartment of Animal Science, University of Tennessee Institute of Agriculture, Knoxville, TN.
Amanda LeeDepartment of Animal Science, University of Tennessee Institute of Agriculture, Knoxville, TN.
Andrea LearLarge Animal Clinical Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, TN.
University of Tennessee at Knoxville · USKnoxville College · USUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mitigation of pain associated with common management procedures is a rising concern among veterinarians, producers and consumers. Nonsteroidal anti-inflammatory drugs are vital compounds for this purpose due to their cost, convenience, and efficacy. A transdermal formulation of flunixin meglumine (FM) was approved for the treatment of pain in cattle; however, the efficacy has yet to be determined for small ruminants. The current study had two aims: 1) to determine the pharmacokinetics of transdermal flunixin meglumine (TD FM) in bucklings and 2) to evaluate pain mitigation by TD FM following castration. To evaluate pharmacokinetics, 12 male goats (mean age = 6 mo) received 2.2 mg/kg of FM IV (

Indexed as

castrationflunixingoatpaintransdermal

Identifiers

PMID33324963
PMCPMC7724925
OpenAlexW3097227658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.