Evidence map›Paper›PMID 33324720›Full record

ArticleOpen forum infectious diseases2020

Diabetes Modifies the Clinic Presentation of Cutaneous Leishmaniasis.

Alexsandro S Lago, Filipe R Lima, Augusto M Carvalho, Camilla Sampaio, Neuza Lago, Luiz H Guimarães, Jamile Lago, Paulo R L Machado, Lucas P Carvalho, Sérgio Arruda and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association between Hypertriglyceridemia and Disease Severity in Visceral Leishmaniasis.The American journal of tropical medicine and hygiene · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Alexsandro S LagoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Filipe R LimaGonçalo Moniz Institute (IGM), Fiocruz, Salvador, Bahia, Brazil.
Augusto M CarvalhoGonçalo Moniz Institute (IGM), Fiocruz, Salvador, Bahia, Brazil.
Camilla SampaioImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Neuza LagoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Luiz H GuimarãesFederal University of Southern Bahia, Teixeira de Freitas, Bahia, Brazil.
Jamile LagoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Paulo R L MachadoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Lucas P CarvalhoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Sérgio ArrudaGonçalo Moniz Institute (IGM), Fiocruz, Salvador, Bahia, Brazil.
Edgar M CarvalhoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador, Bahia, Brazil.
Fundação Oswaldo Cruz · BRComplexo Hospitalar Universitário Professor Edgard Santos · BRUniversidade Federal da Bahia · BRUniversidade Federal do Sul da Bahia · BR

Funding

Inflammation in the Pathogenesis of Disseminated LeishmaniasisU01AI136032 · NIAID · FEDERAL UNIVERSITY OF BAHIA · PI CARVALHO, EDGAR M · 2017 to 2021
$1.6M
NIAID NIH HHS U01 AI136032
6 · The paper itself

Abstract

backgroundCutaneous leishmaniasis (CL) caused by

methodsThe participants were 36 DM patients with CL and 36 patients with CL without DM, matched by age and gender. The diagnosis of CL was performed by documentation of DNA of

resultsThere was no difference in the majority of the clinical variables between the groups, and the cure rate in patients with CL and DM (67%) was similar to that observed in CL patients (56%;

conclusionsDM modifies the clinical presentation of CL, enhances pro-inflammatory cytokine production, and impairs response to antimony therapy.

Indexed as

cutaneous leishmaniasisdiabetesdiabetes mellitusimmune responseleishmaniasistegumentary leishmaniasis

Identifiers

PMID33324720
PMCPMC7724508
OpenAlexW3111580482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.