Evidence map›Paper›PMID 33324339›Full record

ArticleFrontiers in neurology2020

Dynamics of Internalization and Intracellular Interaction of Tau Antibodies and Human Pathological Tau Protein in a Human Neuron-Like Model.

Dov B Shamir, Yan Deng, Qian Wu, Swananda Modak, Erin E Congdon, Einar M Sigurdsson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Targeting Endogenous Tau in Seeded Tauopathy Models Inhibits Tau Spread.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dov B ShamirDepartment of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.
Yan DengMicroscopy Core, New York University Grossman School of Medicine, New York, NY, United States.
Qian WuDepartment of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.
Swananda ModakDepartment of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.
Erin E CongdonDepartment of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.
Einar M SigurdssonDepartment of Neuroscience and Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, United States.
New York University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Research Resource for Human Organs and Tissues (U42)U42OD011158 · OD · NATIONAL DISEASE RESEARCH INTERCHANGE · PI BELL, THOMAS J · 2012 to 2025
$25.0M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2012 to 2014
$16.8M
Research Supplement to Promote Diversity in Health-Related ResearchR01AG032611 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Einar M Sigurdsson · 2008 to 2026
$9.7M
Epitope-Specific Targeting of Tau Aggregates.R01NS077239 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Einar M Sigurdsson · 2011 to 2026
$7.9M
Restoring Animal Research Resources Lost Due to Super Storm SandyR24OD018339 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEVY, DAVID E · 2014 to 2014
$6.7M
Immune Therapy for AD plaques and Tangles in Tg MiceR01AG020197 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SIGURDSSON, EINAR M · 2001 to 2013
$2.8M
Training Program in NeuroscienceT32MH096331 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KLANN, ERIC, RUDY, BERNARDO · 2011 to 2019
$2.6M
Restoring Biospecimen Research Resources Lost Due to Super Storm SandyR24OD018340 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEVY, DAVID E · 2014 to 2014
$2.5M
Training Program in NeuroscienceT32NS069514 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BLOOMFIELD, STEWART ALLEN, KLANN, ERIC · 2010 to 2010
$205k
NCATS NIH HHS UL1 TR000038NCI NIH HHS P30 CA016087NIA NIH HHS R01 AG020197NIA NIH HHS R01 AG032611NIH HHS R24 OD018339NIH HHS R24 OD018340NIH HHS U42 OD011158NIMH NIH HHS T32 MH096331NINDS NIH HHS R01 NS077239NINDS NIH HHS T32 NS069514
6 · The paper itself

Abstract

We and others have shown in various

Indexed as

Alzheimer's diseaseantibodiesimmunotherapieslive imagingPHFtau

Identifiers

PMID33324339
PMCPMC7727311
OpenAlexW3107593922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.