Evidence map›Paper›PMID 33324332›Full record

ReviewFrontiers in neurology2020

Effects of Noise Exposure on the Vestibular System: A Systematic Review.

Courtney Elaine Stewart, Avril Genene Holt, Richard A Altschuler, Anthony Thomas Cacace, Courtney D Hall, Owen D Murnane, W Michael King, Faith W Akin

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06729632 (Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06729632 narecruitingnot on this mapstarted 2024, after this paper: background citation

Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss

TypeinterventionalSponsorRestorear Devices LLCRan2024 to 2027Enrolled116ConditionsNoise Exposure, Noise-induced Hearing Loss, Noise, Adverse EffectArmsCold pack-delivered mild therapeutic hypothermia
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Video Head Impulse test findings in young adults with long-term use of Personal Listening Devices.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Article
  5. The Effect of Listening to Auditory Content using Headphones on Static and Dynamic Balance among Young Females Aged 18-25 Years.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  6. Article
  7. Article
  8. Optimal Frequency for cVEMP in Users of Personal Listening Devices.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  9. Secondary Meniere's Syndrome Following Excessive Noise Exposure.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Role of Video Head Impulse Test to Assess Noise Exposure.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  16. Article
  17. Review
  18. Review
  19. Noise-Induced Hearing Loss.Journal of clinical medicine · 2023
    Review
  20. Peripheral vestibular loss in noise-exposed firefighters.Frontiers in integrative neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Courtney Elaine StewartUniversity of Michigan Department of Otolaryngology/Head-Neck Surgery, Kresge Hearing Research Institute, Ann Arbor, MI, United States.
Avril Genene HoltDepartment of Ophthalmology Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI, United States.
Richard A AltschulerUniversity of Michigan Department of Otolaryngology/Head-Neck Surgery, Kresge Hearing Research Institute, Ann Arbor, MI, United States.
Anthony Thomas CacaceDepartment of Communication Sciences and Disorders, Wayne State University, Detroit, MI, United States.
Courtney D HallDepartment of Rehabilitative Sciences, Doctor of Physical Therapy Program, East Tennessee State University, Johnson City, TN, United States.
Owen D MurnaneDepartment of Audiology and Speech-Language Pathology, East Tennessee State University, Johnson City, TN, United States.
W Michael KingUniversity of Michigan Department of Otolaryngology/Head-Neck Surgery, Kresge Hearing Research Institute, Ann Arbor, MI, United States.
Faith W AkinDepartment of Audiology and Speech-Language Pathology, East Tennessee State University, Johnson City, TN, United States.
East Tennessee State University · USUniversity of Michigan–Ann Arbor · USWayne State University · USVA Ann Arbor Healthcare System · US

Funding

Sensory Mechanisms and Disorders - Administrative SupplementT32DC000011 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael Thomas Roberts · 1989 to 2026
$9.5M
Noise-Induced Synaptic Loss and Vestibular DysfunctionR01DC018003 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KING, WILLIAM M · 2020 to 2023
$2.9M
Sound Evoked Eye and Head Movements Mediated by Vestibulo-Collic and Vestibulo-Ocular Reflex (VOR, VCR) Pathways: a Physiological Basis for Noise Induced Vestibular Loss (NIVL)R21DC015097 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KING, WILLIAM M · 2016 to 2017
$418k
Noise-Induced Synaptic Loss and Vestibular DysfunctionR56DC018003 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KING, WILLIAM M · 2019 to 2019
$156k
The Role of Irregular Vestibular Afferents in Spinal Motor ControlF32DC017063 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEWART, COURTNEY ELAINE · 2018 to 2018
$59k
The Effect of Noise Exposure on the Vestibular SystemI01RX001986 · VA · JAMES H QUILLEN VA MEDICAL CENTER · PI AKIN, FAITH WURM, HOLT, AVRIL GENENE · 2016 to 2021
–
Evaluation of noise-induced injury and restorative agents in the vestibular peripheryIK2RX003271 · VA · VETERANS HEALTH ADMINISTRATION · PI STEWART, COURTNEY ELAINE · 2020 to 2024
–
Development of Effective Strategies for Tinnitus Diagnosis and TreatmentI01RX001095 · VA · JOHN D DINGELL VA MEDICAL CENTER · PI HOLT, AVRIL GENENE · 2014 to 2017
–
NIDCD NIH HHS F32 DC017063NIDCD NIH HHS R01 DC018003NIDCD NIH HHS R21 DC015097NIDCD NIH HHS R56 DC018003NIDCD NIH HHS T32 DC000011RRD VA I01 RX001095RRD VA I01 RX001986RRD VA IK2 RX003271
6 · The paper itself

Abstract

Despite our understanding of the impact of noise-induced damage to the auditory system, much less is known about the impact of noise exposure on the vestibular system. In this article, we review the anatomical, physiological, and functional evidence for noise-induced damage to peripheral and central vestibular structures. Morphological studies in several animal models have demonstrated cellular damage throughout the peripheral vestibular system and particularly in the otolith organs; however, there is a paucity of data on the effect of noise exposure on human vestibular end organs. Physiological studies have corroborated morphological studies by demonstrating disruption across vestibular pathways with otolith-mediated pathways impacted more than semicircular canal-mediated pathways. Similar to the temporary threshold shifts observed in the auditory system, physiological studies in animals have suggested a capacity for recovery following noise-induced vestibular damage. Human studies have demonstrated that diminished sacculo-collic responses are related to the severity of noise-induced hearing loss, and dose-dependent vestibular deficits following noise exposure have been corroborated in animal models. Further work is needed to better understand the physiological and functional consequences of noise-induced vestibular impairment in animals and humans.

Indexed as

continuous noiseimpulse noisenoise-induced vestibular losssaccule and utriclesemicircular canalsvestibular nuclear complexvestibular system

Identifiers

PMID33324332
PMCPMC7723874
OpenAlexW3110632032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.