Evidence map›Paper›PMID 33324149›Full record

ReviewFrontiers in neuroscience2020

Organ Cultures for Retinal Diseases.

José Hurst, Agnes Fietz, Teresa Tsai, Stephanie C Joachim, Sven Schnichels

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Transcriptomic Analysis of Organotypic Porcine Retina Cultures.International journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Commentary: Organ Cultures for Retinal Diseases.Frontiers in neuroscience · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

José HurstCenter for Ophthalmology, University Eye Hospital, University of Tübingen, Tübingen, Germany.
Agnes FietzCenter for Ophthalmology, University Eye Hospital, University of Tübingen, Tübingen, Germany.
Teresa TsaiExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.
Stephanie C JoachimExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.
Sven SchnichelsCenter for Ophthalmology, University Eye Hospital, University of Tübingen, Tübingen, Germany.
University Hospitals of the Ruhr-University of Bochum · DEUniversity of Tübingen · DESTZ eyetrial · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The successful development of novel therapies is closely linked with understanding the underlying pathomechanisms of a disease. To do so, model systems that reflect human diseases and allow for the evaluation of new therapeutic approaches are needed. Yet, preclinical animal studies often have limited success in predicting human physiology, pathology, and therapeutic responses. Moreover, animal testing is facing increasing ethical and bureaucratic hurdles, while human cell cultures are limited in their ability to represent

Indexed as

age-related macular degenerationcentral artery occlusionex vivoglaucomaretinal organ cultureretinitis pigmentosa

Identifiers

PMID33324149
PMCPMC7724035
OpenAlexW3106742324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.