Evidence map›Paper›PMID 33324110›Full record

ArticleClinical epidemiology2020

Physical Activity as an Effect Modifier of the Association Between Obesity and Venous Thromboembolism: A Danish Population-Based Cohort Study.

Henrik Solli, Morten Olsen, Finn Breinholt Larsen, Lars Pedersen, Morten Schmidt

Open access · goldAbstract read
In one paragraph

Article in Clinical epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Henrik SolliDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-7559-091X
Morten OlsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Finn Breinholt LarsenDEFACTUM, Social & Health Services and Labour Market, Central Denmark Region, Aarhus, Denmark.
Lars PedersenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Morten SchmidtDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-4935-4059
Aarhus University Hospital · DKCentral Denmark Region · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObesity is an established risk factor for venous thromboembolism (VTE), while studies on physical inactivity and VTE risk show conflicting results. We examined whether physical activity modified the association between obesity and VTE. PATIENTS AND

methodsWe conducted a population-based cohort study by combining data on outcome diagnoses, comorbidities and medication from nationwide registries with self-reported lifestyle data from an extensive Danish lifestyle questionnaire (2001-2015). We computed incidence rates (IRs) and hazard ratios (HRs) of VTE for categories of body mass index (BMI), among the total study population (n=57,523) and for physically active (n=25,387) and inactive individuals (n=30,902) separately.

resultsObesity (BMI ≥30 kg/m

conclusionPhysical activity acts as an effect measure modifier of the association between obesity and VTE. Thus, physical activity reduced the absolute rate of VTE among obese individuals but increased the relative rate of VTE among obese compared with normal weight individuals.

Indexed as

epidemiologyexerciseobesitysurveys and questionnairesvenous thromboembolism

Identifiers

PMID33324110
PMCPMC7733393
OpenAlexW3113145298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.