ArticleClinical, cosmetic and investigational dermatology2020
The Interaction of Age and Anatomical Region Influenced Skin Biophysical Characteristics of Chinese Women.
Article in Clinical, cosmetic and investigational dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Age-Associated Differences in Facial Skin Structure in Chinese Women: a Cross-Sectional Study.Dermatology and therapy · 2026Article
- Skin aging: mechanisms, evaluation, and rejuvenation.The EMBO journal · 2026Review
- Adipocytes as core drivers of skin aging and novel targets for regeneration.Biogerontology · 2026Review
- Physiological Differences in Sebum Composition in Regularly Menstruating Healthy Women.The Journal of dermatology · 2025Article
- Ultra-Performance Liquid Chromatography-Quadrupole-Time-of-Flight-Mass Spectrometry-Based Analysis of Facial Physiological Parameters and Lipid Composition of Between Sensitive Skin of Women Aged 36-42 and 43-49 Year.Life (Basel, Switzerland) · 2025Article
- Epidermal and dermal hydration in relation to skin color parameters.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Skin biophysical parameters and serum dermokine levels in airline pilots: a comparative study with office workers.Postepy dermatologii i alergologii · 2023Article
- Article
- Epidermal Barrier Function and Skin Homeostasis in Atopic Dermatitis: The Impact of Age.Life (Basel, Switzerland) · 2022Article
- Impact of Water Exposure and Temperature Changes on Skin Barrier Function.Journal of clinical medicine · 2022Article
- Facial Skin Aging Stages in Chinese Females.Frontiers in medicine · 2022Article
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Authors and funding
6 authors.
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Abstract
backgroundAgeing is an inevitable physiology process of humans, and skin biophysical parameters change owing to genetic and environmental factors in different ethnic populations.
aimTo gain comprehensive data on the skin biophysical parameters of different anatomical regions and to explore the change trend of the skin characteristics associated with age for the indicated regions by generalized additive model.
methodsWe measured various skin biophysical parameters on forehead, cheek, chin and inner forearm of 178 Chinese women aged between 20 and 64 years living in Beijing. These parameters comprised skin hydration, transepidermal water loss (TEWL), sebum content, erythema index (EI), melanin index (MI), L*a*b* values, individual typology angle (ITA) and pH, which were quantified by non-invasive instruments.
resultsComparing the skin parameters among the four test areas, we observed that the hydration, TEWL, EI and a* values were significantly higher for the face than for the forearm, but the L* and ITA values were just the opposite. The cheek was the lightest and brightest region with lowest sebum content, while the chin was much darker and the forehead was yellowish. Considering the change of the skin parameters with age, TEWL, sebum content and melanin and erythema indices had a linear relationship with age, whereas skin hydration, L, a, b, ITA and pH values exhibited a non-monotonic relationship. The turning points of these curves appeared almost at the thirties, showing the lightest and evenest skin color and more hydration, with lower pH values.
conclusionThis study indicates that the skin biophysical characteristics of Chinese women were significantly affected by age and body regions.
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