Evidence map›Paper›PMID 33324073›Full record

ArticleOncoTargets and therapy2020

Inhibition of CSRP2 Promotes Leukemia Cell Proliferation and Correlates with Relapse in Adults with Acute Myeloid Leukemia.

Shujuan Wang, Yu Zhang, Yajun Liu, Ruyue Zheng, Zhenzhen Wu, Yi Fan, Mengya Li, Menglin Li, Tao Li, Yafei Li and 3 more

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. [Role and mechanism of cysteine and glycine-rich protein 2 in the malignant progression of neuroblastoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Shujuan Wang *Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Yu Zhang *Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Yajun LiuDepartment of Orthopaedics, Brown University, Warren Alpert Medical School/Rhode Island Hospital, Rhode Island, RI, USA.
Ruyue ZhengDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.ORCID 0000-0001-6196-0513
Zhenzhen WuDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Yi FanDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Mengya LiDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Menglin LiDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Tao LiDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Yafei LiDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Zhongxing JiangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Chong WangDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Yanfang LiuDepartment of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.ORCID 0000-0002-0568-737X
First Affiliated Hospital of Zhengzhou University · CNBrown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRelapse is a major obstacle in the treatment of acute myeloid leukemia (AML). Refinement of risk stratification may aid the identification of patients who are likely to relapse. Abnormal cysteine and glycine-rich protein 2 (CSRP2) has been implicated in various cancers, but its function remains unclear. The purpose of this study was to explore the role of CSRP2 in predicting adult AML recurrence.

methodsRT-PCR was used to detect the expression of

results

conclusionIn summary,

Indexed as

acute myeloid leukemiacAMP-regulatory element-binding proteincysteine and glycine-rich protein 2proliferationrelapse

Identifiers

PMID33324073
PMCPMC7733086
OpenAlexW3110884814

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.