Evidence map›Paper›PMID 33323548›Full record

ArticleAging2020

Upregulation of HOTAIRM1 increases migration and invasion by glioblastoma cells.

Peng Xie, Xiang Li, Rui Chen, Yue Liu, DaChao Liu, Wenguang Liu, Gang Cui, Jinjing Xu

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  8. Journal of Cancer · 2024
    Article
  9. Review
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  12. Article
  13. Article
  14. Article
  15. The Roles Played by Long Non-Coding RNAs in Glioma Resistance.International journal of molecular sciences · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Peng XieDepartment of Neurosurgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, Jiangsu Province, China.
Xiang LiDepartment of Oncology, Huaian Hospital of Huaian District, Huai'an, Jiangsu Province, China.
Rui ChenDepartment of Neurology, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, Jiangsu Province, China.
Yue LiuDepartment of Intensive Care Unit, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, Jiangsu Province, China.
DaChao LiuDepartment of Image, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, Jiangsu Province, China.
Wenguang LiuDepartment of Neurosurgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, The Second People's Hospital of Huai'an, Huai'an, Jiangsu Province, China.
Gang CuiDepartment of Neurosurgery, First Affiliated Hospital of Soochow University, Suzhou, China.
Jinjing XuGalactophore Department, Jiangsu Huai'an Maternity and Children Hospital, Huai'an, Jiangsu Province, China.
Xuzhou Medical College · CNSecond People’s Hospital of Huai’an · CNFirst Affiliated Hospital of Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) promote invasion and migration by glioblastoma (GBM) cells. In this study, quantitative real-time polymerase chain reaction was used to detect expression levels of the lncRNA HOTAIRM1 in GBM tissue samples and cells. The function of HOTAIRM1 was examined using wound healing assays, transwell assays, and

Indexed as

AnimalsAntigens, CDBiomarkers, TumorBrain NeoplasmsCadherinsCell Line, TumorCell MovementGene Expression Regulation, NeoplasticGene Knockdown TechniquesGlioblastomaHumansMiceMice, Inbred BALB CMicroRNAsNeoplasm InvasivenessSnail Family Transcription FactorsAntigens, CDBiomarkers, TumorCadherinsCDH1 protein, humanlong non-coding RNA HOTAIRM1, humanMicroRNAsMIRN153 microRNA, humanSNAI2 protein, humanSnail Family Transcription FactorsgliomaHOTAIRM1miR-153-5pSNAI2

Identifiers

PMID33323548
PMCPMC7880397
OpenAlexW3111634270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.