Evidence map›Paper›PMID 33323514›Full record

ArticlemBio2020

Neonatal Mouse Gut Metabolites Influence Cryptosporidium parvum Infection in Intestinal Epithelial Cells.

Kelli L VanDussen, Lisa J Funkhouser-Jones, Marianna E Akey, Deborah A Schaefer, Kevin Ackman, Michael W Riggs, Thaddeus S Stappenbeck, L David Sibley

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Early life infection withGut microbes · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Microbiota assembly of specific pathogen-free neonatal mice.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Dendritic Cells andMicroorganisms · 2023
    Review
  14. Article
  15. Early immune and host cell responses toFrontiers in parasitology · 2023
    Article
  16. Article
  17. Effect of Caging onMicroorganisms · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kelli L VanDussen *Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Lisa J Funkhouser-Jones *Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Marianna E AkeyDepartment of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA.
Deborah A SchaeferSchool of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, USA.
Kevin AckmanSchool of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, USA.
Michael W RiggsSchool of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, USA.
Thaddeus S StappenbeckDepartment of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA.
L David SibleyDepartment of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA sibley@wustl.edu.ORCID 0000-0001-7110-0285
Washington University in St. Louis · USUniversity of Arizona · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Effect of Microbial Metabolites on Growth of CryptosporidiumR01AI145496 · NIAID · WASHINGTON UNIVERSITY · PI SIBLEY, L. DAVID · 2020 to 2023
$2.7M
DEFINING THE BASIS OF EPITHELIAL DEFECTS IN CROHN'S DISEASE PATIENTSK01DK109081 · NIDDK · WASHINGTON UNIVERSITY · PI VANDUSSEN, KELLI LYNN · 2016 to 2020
$737k
NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NIAID NIH HHS R01 AI145496NIDDK NIH HHS K01 DK109081
6 · The paper itself

Abstract

The protozoan parasite

Indexed as

Gastrointestinal MicrobiomeAnimalsAnimals, NewbornBacteriaCryptosporidiosisCryptosporidium parvumDisease Models, AnimalEpithelial CellsFatty AcidsFemaleHumansIntestinal MucosaMaleMiceMice, Inbred ICRFatty Acids16S rRNACryptosporidium parvumenteric infectionessential nutrientfatty acidmetabolitemicrobiota

Identifiers

PMID33323514
PMCPMC7773987
OpenAlexW3111085242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.