Evidence map›Paper›PMID 33323509›Full record

ArticlemBio2020

The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets.

E Keats Shwab, Praveen R Juvvadi, Greg Waitt, Shareef Shaheen, John Allen, Erik J Soderblom, Benjamin G Bobay, Yohannes G Asfaw, M Arthur Moseley, William J Steinbach

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Multifunctional Roles of Autophagy in Fungi.Journal of fungi (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

E Keats ShwabDivision of Pediatric Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Praveen R JuvvadiDivision of Pediatric Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Greg WaittDuke Proteomics Core Facility, Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, USA.
Shareef ShaheenDivision of Pediatric Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
John AllenDivision of Pediatric Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Erik J SoderblomDuke Proteomics Core Facility, Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, USA.
Benjamin G BobayDuke University NMR Center, Duke University Medical Center, Durham, North Carolina, USA.
Yohannes G AsfawDepartment of Laboratory Animal Resources, Duke University Medical Center, Durham, North Carolina, USA.
M Arthur MoseleyDuke Proteomics Core Facility, Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, USA.
William J SteinbachDivision of Pediatric Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA bill.steinbach@duke.edu.
Duke Medical Center · USDuke University · USDuke University Hospital · US

Funding

Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass SpectrometerS10OD024999 · OD · DUKE UNIVERSITY · PI MOSELEY, MARTIN ARTHUR · 2018 to 2018
$600k
Phosphoproteomic identification of Aspergillus fumigatus virulence-associated protein kinase A downstream effectorsR21AI132911 · NIAID · DUKE UNIVERSITY · PI JUVVADI, PRAVEEN RAO, STEINBACH, WILLIAM J · 2018 to 2019
$440k
NIAID NIH HHS R21 AI132911NIH HHS S10 OD024999
6 · The paper itself

Abstract

Protein kinase A (PKA) signaling plays a critical role in the growth and development of all eukaryotic microbes. However, few direct targets have been characterized in any organism. The fungus

Indexed as

AnimalsAspergillosisAspergillus fumigatusCyclic AMP-Dependent Protein KinasesFungal ProteinsHumansMicePhosphorylationProteomeProteomicsVirulenceCyclic AMP-Dependent Protein KinasesFungal ProteinsProteomeAspergillusfilamentous fungifungal pathogenprotein kinase Aprotein phosphorylationproteomics

Identifiers

PMID33323509
PMCPMC7773993
OpenAlexW3111915199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.