Evidence map›Paper›PMID 33323442›Full record

ArticleBMJ open2020

Double-blind RCT of fish oil supplementation in pregnancy and lactation to improve the metabolic health in children of mothers with overweight or obesity during pregnancy: study protocol.

Vidit V Satokar, Wayne S Cutfield, José G B Derraik, Matire Harwood, Karaponi Okasene-Gafa, Kathryn Beck, David Cameron-Smith, Justin M O'Sullivan, Gerhard Sundborn, Shikha Pundir and 2 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 5 countries.

Vidit V SatokarLiggins Institute, University of Auckland, Auckland, New Zealand.
Wayne S CutfieldLiggins Institute, University of Auckland, Auckland, New Zealand.
José G B DerraikLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-1226-1956
Matire HarwoodNational Hauora Coalition, Auckland, New Zealand.
Karaponi Okasene-GafaDepartment of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.
Kathryn BeckSchool of Sport Exercise and Nutrition, Massey University, Auckland, New Zealand.
David Cameron-SmithLiggins Institute, University of Auckland, Auckland, New Zealand.
Justin M O'SullivanLiggins Institute, University of Auckland, Auckland, New Zealand.
Gerhard SundbornDepartment of Pacific Health, University of Auckland, Auckland, New Zealand.
Shikha PundirLiggins Institute, University of Auckland, Auckland, New Zealand.
R Preston MasonBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Benjamin B AlbertLiggins Institute, University of Auckland, Auckland, New Zealand b.albert@auckland.ac.nz.ORCID 0000-0003-0498-3473
University of Auckland · NZAgency for Science, Technology and Research · SGBrigham and Women's Hospital · USMassey University · NZUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMaternal obesity during pregnancy is associated with adverse changes in body composition and metabolism in the offspring. We hypothesise that supplementation during pregnancy of overweight and obese women may help prevent the development of greater adiposity and metabolic dysfunction in children. Previous clinical trials investigating fish oil supplementation in pregnancy on metabolic outcomes and body composition of the children have not focused on the pregnancies of overweight or obese women. METHODS AND ANALYSIS: A double-blind randomised controlled trial of fish oil (providing 3 g/day of n-3 polyunsaturated fatty acids) versus an equal volume of olive oil (control) taken daily from recruitment until birth, and in breastfeeding mothers, further continued for 3 months post partum. Eligible women will have a singleton pregnancy at 12-20 weeks' gestation and be aged 18-40 years with body mass index ≥25 kg/m ETHICS AND DISSEMINATION: This trial was approved by the Northern A Health and Disabilities Ethics Committee, New Zealand Ministry of Health (17/NTA/154). Results will be published in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: ACTRN12617001078347p; Pre-results.

Indexed as

Breast FeedingFish OilsAdolescentAdultChildDietary SupplementsDouble-Blind MethodFemaleHumansInfantLactationMothersNew ZealandObesityOverweightPregnancyFish Oilsnutrition & dieteticsobstetricspaediatricspreventive medicine

Identifiers

PMID33323442
PMCPMC7745511
OpenAlexW3110926714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.