Evidence map›Paper›PMID 33323004›Full record

ArticleGut microbes2020

From correlation to causality: the case of

Matthias Van Hul, Tiphaine Le Roy, Edi Prifti, Maria Carlota Dao, Adrien Paquot, Jean-Daniel Zucker, Nathalie M Delzenne, Giulio Muccioli, Karine Clément, Patrice D Cani

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 4 pooled it
29.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 4 syntheses or guidelines pooled it, 210 citations in OpenAlex.

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  11. Consumption of yacon flour and energy-restricted diet increased the relative abundance of intestinal bacteria in obese adults.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Matthias Van HulMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université Catholique de Louvain , Brussels, Belgium.ORCID 0000-0002-5503-107X
Tiphaine Le RoyMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université Catholique de Louvain , Brussels, Belgium.ORCID 0000-0002-0874-1490
Edi PriftiInstitut de Recherche et Developpement, IRD, Sorbonne Unive.rsity, UMMISCO , Bondy, France.ORCID 0000-0001-8861-1305
Maria Carlota DaoSorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (Nutriomics) Research Unit , Paris, France.
Adrien PaquotBioanalysis and Pharmacology of Bioactive Lipids Research Group, Louvain Drug Research Institute, UCLouvain, Université Catholique de Louvain , Brussels, Belgium.
Jean-Daniel ZuckerInstitut de Recherche et Developpement, IRD, Sorbonne Unive.rsity, UMMISCO , Bondy, France.ORCID 0000-0002-5597-7922
Nathalie M DelzenneMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université Catholique de Louvain , Brussels, Belgium.ORCID 0000-0003-2115-6082
Giulio MuccioliBioanalysis and Pharmacology of Bioactive Lipids Research Group, Louvain Drug Research Institute, UCLouvain, Université Catholique de Louvain , Brussels, Belgium.ORCID 0000-0002-1600-9259
Karine ClémentSorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (Nutriomics) Research Unit , Paris, France.ORCID 0000-0002-2489-3355
Patrice D CaniMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université Catholique de Louvain , Brussels, Belgium.ORCID 0000-0003-2040-2448
Inserm · FRWalloon Excellence in Lifesciences and Biotechnology · BEUCLouvain · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbes are considered as major factors contributing to human health. Nowadays, the vast majority of the data available in the literature are mostly exhibiting negative or positive correlations between specific bacteria and metabolic parameters. From these observations, putative detrimental or beneficial effects are then inferred.

Indexed as

AdultAkkermansiaAnimalsCholesterol, HDLDiabetes MellitusDiet, High-FatEubacterialesGastrointestinal MicrobiomeHumansInsulin ResistanceLipid MetabolismMaleMetagenomeMiceMice, Inbred C57BLMiddle AgedCholesterol, HDLAkkermansia muciniphilahigh-fat diethuman cohortmiceobesitySubdoligranulumsubdoligranulum variabile

Identifiers

PMID33323004
PMCPMC7744154
OpenAlexW3112267312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.