Evidence map›Paper›PMID 33322953›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1

Olga Ciupak, Mateusz Daśko, Karol Biernacki, Janusz Rachon, Maciej Masłyk, Konrad Kubiński, Aleksandra Martyna, Sebastian Demkowicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Olga CiupakDepartment of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Gdańsk, Poland.
Mateusz DaśkoDepartment of Inorganic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Gdańsk, Poland.ORCID https://orcid.org/0000-0002-3367-6491
Karol BiernackiDepartment of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Gdańsk, Poland.ORCID https://orcid.org/0000-0003-3036-8693
Janusz RachonDepartment of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Gdańsk, Poland.ORCID https://orcid.org/0000-0001-5377-8228
Maciej MasłykDepartment of Molecular Biology, The John Paul II Catholic University of Lublin, Lublin, Poland.
Konrad KubińskiDepartment of Molecular Biology, The John Paul II Catholic University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0001-6870-845X
Aleksandra MartynaDepartment of Molecular Biology, The John Paul II Catholic University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-7602-002X
Sebastian DemkowiczDepartment of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Gdańsk, Poland.ORCID https://orcid.org/0000-0002-4252-4297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work, we report a new class of potent steroid sulphatase (STS) inhibitors based on 6-(1-phenyl-1

Indexed as

Dose-Response Relationship, DrugEnzyme InhibitorsHumansMCF-7 CellsMolecular StructureSteryl-SulfataseStructure-Activity RelationshipSulfonic AcidsEnzyme InhibitorsSteryl-Sulfatasesulfamic acidSulfonic Acidsbreast cancerhormone-dependent cancerSteroid sulphataseSTS inhibitorstriazoles

Identifiers

PMID33322953
PMCPMC7744152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.