Evidence map›Paper›PMID 33322915›Full record

ArticleJournal of the American Heart Association2021

Disparities in Cardiovascular Disease Outcomes Among Pregnant and Post-Partum Women.

Mohamed M Gad, Islam Y Elgendy, Ahmed N Mahmoud, Anas M Saad, Toshiaki Isogai, Isadora Sande Mathias, Rabel Misbah Rameez, Johnny Chahine, Hani Jneid, Samir R Kapadia

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06920563 (Remote Postpartum Blood Pressure Monitoring and Cardiovascular Education to Reduce Emergency Department Visits, Re-admissions and Adverse Cardiovascular Outcomes in Hypertensive Disorder of Pregnancy), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06920563 narecruitingnot on this mapstarted 2025, after this paper: background citation

Remote Postpartum Blood Pressure Monitoring and Cardiovascular Education to Reduce Emergency Department Visits, Re-admissions and Adverse Cardiovascular Outcomes in Hypertensive Disorder of Pregnancy

TypeinterventionalSponsorOchsner Health SystemRan2025 to 2026Enrolled296ConditionsPre-Eclampsia, Complicating Pregnancy, Gestational HypertensionArmsVideo, Text Reminder, Blood pressure threshold
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Bayesian zero-inflated spatially varying coefficients model for overdispersed binomial data.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Breastfeeding Practices in Patients with Heart Disease Stratified by Area Deprivation Index.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Mohamed M GadCleveland Clinic Foundation Cleveland OH.
Islam Y ElgendyDivision of Cardiology Weill Cornell Medicine-Qatar Doha Qatar.
Ahmed N MahmoudDepartment of Cardiovascular Medicine Harrington Heart and Vascular InstituteCase Western Reserve University Cleveland OH.
Anas M SaadCleveland Clinic Foundation Cleveland OH.
Toshiaki IsogaiCleveland Clinic Foundation Cleveland OH.
Isadora Sande MathiasCleveland Clinic Foundation Cleveland OH.
Rabel Misbah RameezDivision of Cardiovascular Medicine University of Michigan Ann Arbor MI.
Johnny ChahineDivision of Cardiology University of Minnesota Minneapolis MN.
Hani JneidSection of Cardiology Baylor School of Medicine Houston TX.
Samir R KapadiaCleveland Clinic Foundation Cleveland OH.
Cleveland Clinic · USBaylor School · USCase Western Reserve University · USUniversity of Michigan · USUniversity of Minnesota · USWeill Cornell Medical College in Qatar · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The incidence of cardiovascular disease among pregnant women is rising in the United States. Data on racial disparities for the major cardiovascular events during pregnancy are limited. Methods and Results Pregnant and post-partum women hospitalized from January 2007 to December 2017 were identified from the Nationwide Inpatient Sample. The outcomes of interest included: in-hospital mortality, myocardial infarction, stroke, pulmonary embolism, and peripartum cardiomyopathy. Multivariate regression analysis was used to assess the independent association between race and in-hospital outcomes. Among 46 700 637 pregnancy-related hospitalizations, 21 663 575 (46.4%) were White, 6 302 089 (13.5%) were Black, and 8 914 065 (19.1%) were Hispanic. The trends of mortality and stroke declined significantly in Black women, but however, were mostly unchanged among White women. The incidence of mortality and cardiovascular morbidity was highest among Black women followed by White women, then Hispanic women. The majority of Blacks (62.3%) were insured by Medicaid while the majority of White patients had private insurance (61.9%). Most of Black women were below-median income (71.2%) while over half of the White patients were above the median income (52.7%). Compared with White women, Black women had the highest mortality with adjusted odds ratio (aOR) of 1.45, 95% CI (1.21-1.73); myocardial infarction with aOR of 1.23, 95% CI (1.06-1.42); stroke with aOR of 1.57, 95% CI (1.41-1.74); pulmonary embolism with aOR of 1.42, 95% CI (1.30-1.56); and peripartum cardiomyopathy with aOR of 1.71, 95 % CI (1.66-1.76). Conclusions Significant racial disparities exist in major cardiovascular events among pregnant and post-partum women. Further efforts are needed to minimize these differences.

Indexed as

Cardiovascular DiseasesHealth Status DisparitiesHospital MortalityPregnancy Complications, CardiovascularPuerperal DisordersAdultDemographyFemaleHealthcare DisparitiesHealth Services Needs and DemandHospitalizationHumansIncidenceMedicaidPregnancySocioeconomic Factorscardiovascular mortalitydisparities in carehealth inequitiespregnancy

Identifiers

PMID33322915
PMCPMC7955477
OpenAlexW3112124438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.