Evidence map›Paper›PMID 33322803›Full record

ArticleMicroorganisms2020

In Vitro and In Vivo Evaluations of β-Lactam/β-Lactamase Mono- and Combined Therapies against Carbapenem-Nonsusceptible Enterobacteriaceae in Taiwan.

Tsung-Ying Yang, Ya-Ju Hsieh, Li-Ting Kao, Guan-Hong Liu, Shao-Hsuan Lian, Liang-Chun Wang, I-Ling Lin, Yu-Tzu Lin, Sheng-Fan Wang, Sung-Pin Tseng and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Tsung-Ying YangDepartment of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Ya-Ju HsiehDepartment of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Li-Ting KaoOrthopedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Guan-Hong LiuDepartment of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Shao-Hsuan LianDepartment of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Liang-Chun WangDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0002-4977-4256
I-Ling LinDepartment of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0001-7022-4315
Yu-Tzu LinDepartment of Medical Laboratory Science and Biotechnology, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-3815-6305
Sheng-Fan WangDepartment of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0002-4183-3872
Sung-Pin TsengDepartment of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Po-Liang LuSchool of Post-Baccalaureate Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0002-7423-6783
Kaohsiung Medical University · TWNational Sun Yat-sen University · TWChina Medical University · TW

Funding

Kaohsiung Medical University Research Center Grant KMU-TC108B03 and KMU-TC109B02Kaohsiung Medical University Research Foundation M109001Ministry of Science and Technology of Taiwan MOST 109-2320-B-037-027National Sun Yat-sen University-Kaohsiung Medical University (NSYSU-KMU) Industry-Academia Collaboration 108KN007National Sun Yat-sen University-Kaohsiung Medical University (NSYSU-KMU) Joint Research Project NSYSUKMU 109-I005
6 · The paper itself

Abstract

Increasing carbapenem resistance rates worldwide underscored the urgent need of novel antimicrobials. Ceftazidime-avibactam and aztreonam-avibactam combinations are developed to combat carbapenem resistance, but biological and geographic variations must be considered for antibiotic susceptibility patterns varied. Thus, we sought to assess the susceptibilities of ceftazidime-avibactam and aztreonam-avibactam against 660 carbapenem-nonsusceptible Enterobacteriaceae isolates (472

Indexed as

combination therapyCR Enterobacteriaceaemolecular epidemiology of antimicrobial resistance

Identifiers

PMID33322803
PMCPMC7764198
OpenAlexW3111122494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.