Evidence map›Paper›PMID 33322750›Full record

ReviewSensors (Basel, Switzerland)2020

Fluorescence Polarization-Based Bioassays: New Horizons.

Olga D Hendrickson, Nadezhda A Taranova, Anatoly V Zherdev, Boris B Dzantiev, Sergei A Eremin

Open access · goldAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
  2. Article
  3. Determination of okadaic acid in scallop using microfluidic-based fluorescence polarization immunoassay.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Article
  14. Identification of novel bromodomain inhibitors ofAntimicrobial agents and chemotherapy · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Rapid determination of domoic acid in seafood by fluorescence polarization immunoassay using a portable analyzer.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Olga D HendricksonA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Nadezhda A TaranovaA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
Anatoly V ZherdevA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0003-3008-2839
Boris B DzantievA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0003-4008-4918
Sergei A EreminA.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.
A N Bach Institute of Biochemistry · RULomonosov Moscow State University · RU

Funding

Russian Science Foundation 20-43-07001
6 · The paper itself

Abstract

Fluorescence polarization holds considerable promise for bioanalytical systems because it allows the detection of selective interactions in real time and a choice of fluorophores, the detection of which the biosample matrix does not influence; thus, their choice simplifies and accelerates the preparation of samples. For decades, these possibilities were successfully applied in fluorescence polarization immunoassays based on differences in the polarization of fluorophore emissions excited by plane-polarized light, whether in a free state or as part of an immune complex. However, the results of recent studies demonstrate the efficacy of fluorescence polarization as a detected signal in many bioanalytical methods. This review summarizes and comparatively characterizes these developments. It considers the integration of fluorescence polarization with the use of alternative receptor molecules and various fluorophores; different schemes for the formation of detectable complexes and the amplification of the signals generated by them. New techniques for the detection of metal ions, nucleic acids, and enzymatic reactions based on fluorescence polarization are also considered.

Indexed as

Biological AssayFluorescent DyesNucleic AcidsFluorescence PolarizationMetalsFluorescent DyesMetalsNucleic Acidsantibodiesaptamersbioreceptorsfluorescence polarizationimmunoassaynucleic acidsportable optical detectorsrotation of moleculesswitched on biosensors

Identifiers

PMID33322750
PMCPMC7764623
OpenAlexW3111905163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.