Evidence map›Paper›PMID 33322747›Full record

ArticleEntropy (Basel, Switzerland)2020

Assessment of Nocturnal Autonomic Cardiac Imbalance in Positional Obstructive Sleep Apnea. A Multiscale Nonlinear Approach.

Daniel Álvarez, C Ainhoa Arroyo, Julio F de Frutos, Andrea Crespo, Ana Cerezo-Hernández, Gonzalo C Gutiérrez-Tobal, Fernando Vaquerizo-Villar, Verónica Barroso-García, Fernando Moreno, Tomás Ruiz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Exploring the Impact of Positional Sleep Apnea in a Turkish Population: Unveiling the Untold Story.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Daniel ÁlvarezPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0003-1027-2395
C Ainhoa ArroyoPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.
Julio F de FrutosPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.
Andrea CrespoPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0002-2709-5797
Ana Cerezo-HernándezPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.
Gonzalo C Gutiérrez-TobalBiomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0002-1237-3424
Fernando Vaquerizo-VillarBiomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain.
Verónica Barroso-GarcíaBiomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0001-5648-206X
Fernando MorenoPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.
Tomás RuizPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0003-4785-7151
Roberto HorneroBiomedical Engineering Group, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0001-9915-2570
Félix Del CampoPneumology Department, Río Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0002-4554-2167
Universidad de Valladolid · ESHospital Universitario Río Hortega · ES

Funding

Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina CB19/01/00012Consejería de Educación de la Junta de Castilla y León Ayuda para financiar la contratación predoctoral de personal investigadorEuropean Regional Development Fund DPI2017-84280-R and RTC-2017-6516-1Gerencia Regional de Salud de Castilla y León GRS 1950/A/19 and INT/M/15/20Ministerio de Ciencia, Innovación y Universidades DPI2017-84280-R and RTC-2017-6516-1Ministerio de Educación, Cultura y Deporte FPU16/02938Sociedad Española de Neumología y Cirugía Torácica 649/2018 and 66/2016
6 · The paper itself

Abstract

Positional obstructive sleep apnea (POSA) is a major phenotype of sleep apnea. Supine-predominant positional patients are frequently characterized by milder symptoms and less comorbidity due to a lower age, body mass index, and overall apnea-hypopnea index. However, the bradycardia-tachycardia pattern during apneic events is known to be more severe in the supine position, which could affect the cardiac regulation of positional patients. This study aims at characterizing nocturnal heart rate modulation in the presence of POSA in order to assess potential differences between positional and non-positional patients. Patients showing clinical symptoms of suffering from a sleep-related breathing disorder performed unsupervised portable polysomnography (PSG) and simultaneous nocturnal pulse oximetry (NPO) at home. Positional patients were identified according to the Amsterdam POSA classification (APOC) criteria. Pulse rate variability (PRV) recordings from the NPO readings were used to assess overnight cardiac modulation. Conventional cardiac indexes in the time and frequency domains were computed. Additionally, multiscale entropy (MSE) was used to investigate the nonlinear dynamics of the PRV recordings in POSA and non-POSA patients. A total of 129 patients (median age 56.0, interquartile range (IQR) 44.8-63.0 years, median body mass index (BMI) 27.7, IQR 26.0-31.3 kg/m

Indexed as

cardiac dynamicsheart rate variabilitymultiscale entropynonlinear analysispositional apnea

Identifiers

PMID33322747
PMCPMC7764670
OpenAlexW3111502547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.