Evidence map›Paper›PMID 33322741›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Hongchan Lee, Tayaba Ismail, Youni Kim, Shinhyeok Chae, Hong-Yeoul Ryu, Dong-Seok Lee, Taeg Kyu Kwon, Tae Joo Park, Taejoon Kwon, Hyun-Shik Lee

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Prdx6 regulatesAnimal cells and systems · 2025
    Article
  3. Article
  4. Glucose-6-Phosphate Dehydrogenase, Redox Homeostasis and Embryogenesis.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Article
  7. Cellular Redox Homeostasis.Antioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hongchan LeeKNU-Center for Nonlinear Dynamics, CMRI, BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.
Tayaba IsmailKNU-Center for Nonlinear Dynamics, CMRI, BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.
Youni KimKNU-Center for Nonlinear Dynamics, CMRI, BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.
Shinhyeok ChaeDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), College of Information-Bio Convergence, Ulsan 44919, Korea.
Hong-Yeoul RyuKNU-Center for Nonlinear Dynamics, CMRI, BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.
Dong-Seok LeeKNU-Center for Nonlinear Dynamics, CMRI, BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0002-7106-1615
Taeg Kyu KwonDepartment of Immunology, School of Medicine, Keimyung University, Daegu 42601, Korea.ORCID 0000-0003-1204-2059
Tae Joo ParkDepartment of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), College of Information-Bio Convergence, Ulsan 44919, Korea.
Taejoon KwonDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), College of Information-Bio Convergence, Ulsan 44919, Korea.ORCID 0000-0002-9794-6112
Hyun-Shik LeeKNU-Center for Nonlinear Dynamics, CMRI, BK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0002-3837-9867
Kyungpook National University · KRUlsan National Institute of Science and Technology · KR

Funding

National Research Foundation of Korea 2020R1A4A1018280, 2018R1A6A1A03025810National Research Foundation of Korea 2020R1F1A1048235
6 · The paper itself

Abstract

Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and is a key antioxidant enzyme in multicellular organisms against oxidative damage. Downregulation of GPx3 affects tumor progression and metastasis and is associated with liver and heart disease. However, the physiological significance of GPx3 in vertebrate embryonic development remains poorly understood. The current study aimed to investigate the functional roles of

Indexed as

apoptosisembryogenesisgpx3posterior developmenttailbud

Identifiers

PMID33322741
PMCPMC7764483
OpenAlexW3112655946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.