Evidence map›Paper›PMID 33322701›Full record

ReviewSensors (Basel, Switzerland)2020

Recent Advances in Cell Adhesive Force Microscopy.

Ying Tu, Xuefeng Wang

Open access · goldAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ying TuDepartment of Physics and Astronomy, Iowa State University, Ames, IA 50011, USA.
Xuefeng WangDepartment of Physics and Astronomy, Iowa State University, Ames, IA 50011, USA.
Iowa State University · US

Funding

Study the role of integrin tension in cell migration, platelet functions and phagocytosisR35GM128747 · NIGMS · UNIVERSITY OF CINCINNATI · PI Xuefeng Wang · 2018 to 2026
$2.8M
National Science Foundation 1825724NIGMS NIH HHS GM128747NIGMS NIH HHS R35 GM128747
6 · The paper itself

Abstract

Cell adhesive force, exerting on the local matrix or neighboring cells, plays a critical role in regulating many cell functions and physiological processes. In the past four decades, significant efforts have been dedicated to cell adhesive force detection, visualization and quantification. A recent important methodological advancement in cell adhesive force visualization is to adopt force-to-fluorescence conversion instead of force-to-substrate strain conversion, thus greatly improving the sensitivity and resolution of force imaging. This review summarizes the recent development of force imaging techniques (collectively termed as cell adhesive force microscopy or CAFM here), with a particular focus on the improvement of CAFM's spatial resolution and the biomaterial choices for constructing the tension sensors used in force visualization. This review also highlights the importance of DNA-based tension sensors in cell adhesive force imaging and the recent breakthrough in the development of super-resolution CAFM.

Indexed as

AdhesivesMechanical PhenomenaMicroscopy, Atomic ForceDNAMechanotransduction, CellularAdhesivesDNAcell adhesioncell adhesive forcecell traction forcecellular force imagingDNAintegrinintegrin tensionmechanobiologymechanotransductionsuper-resolutiontension sensor

Identifiers

PMID33322701
PMCPMC7763046
OpenAlexW3111753613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.