Evidence map›Paper›PMID 33322692›Full record

ReviewInternational journal of molecular sciences2020

Differential Co-Expression Analyses Allow the Identification of Critical Signalling Pathways Altered during Tumour Transformation and Progression.

Aurora Savino, Paolo Provero, Valeria Poli

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aurora SavinoMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, 10126 Turin, Italy.ORCID 0000-0002-0783-7191
Paolo ProveroDepartment of Neurosciences "Rita Levi Montalcini", University of Turin, Corso Massimo D'Ázeglio 52, 10126 Turin, Italy.ORCID 0000-0001-8664-8630
Valeria PoliMolecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, 10126 Turin, Italy.

Funding

Associazione Italiana per la Ricerca sul Cancro AIRC IG16930Ministero dell'Istruzione, dell'Università e della Ricerca MIUR-PRIN 2017Regione Piemonte Deflect POLV_SALU_BEN_18_01the Truus and Gerrit van Riemsdijk Foundation, Liechtenstein 2011-2015
6 · The paper itself

Abstract

Biological systems respond to perturbations through the rewiring of molecular interactions, organised in gene regulatory networks (GRNs). Among these, the increasingly high availability of transcriptomic data makes gene co-expression networks the most exploited ones.

Indexed as

Gene Regulatory NetworksAlgorithmsComputational BiologyDisease ProgressionGene Expression ProfilingGene Expression Regulation, NeoplasticHumansNeoplasmsSignal TransductionTranscriptomebioinformaticsbiological networkscancercomputational biologydifferential co-expressiontumour progression

Identifiers

PMID33322692
PMCPMC7764314

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.