Evidence map›Paper›PMID 33322632›Full record

ArticleFoods (Basel, Switzerland)2020

Biomanufacturing of Tomato-Derived Nanovesicles.

Ramesh Bokka, Anna Paulina Ramos, Immacolata Fiume, Mauro Manno, Samuele Raccosta, Lilla Turiák, Simon Sugár, Giorgia Adamo, Tamás Csizmadia, Gabriella Pocsfalvi

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ramesh BokkaExtracellular Vesicles and Mass Spectrometry Group, Institute of Biosciences and BioResources, National Research Council of Italy, 80131 Naples, Italy.
Anna Paulina RamosExtracellular Vesicles and Mass Spectrometry Group, Institute of Biosciences and BioResources, National Research Council of Italy, 80131 Naples, Italy.
Immacolata FiumeExtracellular Vesicles and Mass Spectrometry Group, Institute of Biosciences and BioResources, National Research Council of Italy, 80131 Naples, Italy.
Mauro MannoInstitute of Biophysics, National Research Council of Italy, 90146 Palermo, Italy.
Samuele RaccostaInstitute of Biophysics, National Research Council of Italy, 90146 Palermo, Italy.ORCID 0000-0001-7775-5928
Lilla TuriákMS Proteomics Research Group, Hungarian Academy of Sciences, Research Centre for Natural Sciences, 1117 Budapest, Hungary.ORCID 0000-0002-2139-8156
Simon SugárMS Proteomics Research Group, Hungarian Academy of Sciences, Research Centre for Natural Sciences, 1117 Budapest, Hungary.
Giorgia AdamoInstitute for Biomedical Research and Innovation, National Research Council of Italy, 90146 Palermo, Italy.
Tamás CsizmadiaDepartment of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0002-2098-9165
Gabriella PocsfalviExtracellular Vesicles and Mass Spectrometry Group, Institute of Biosciences and BioResources, National Research Council of Italy, 80131 Naples, Italy.ORCID 0000-0001-6065-3853

Funding

Horizon 2020 Framework Programme 798576
6 · The paper itself

Abstract

Micro- and nano-sized vesicles (MVs and NVs, respectively) from edible plant resources are gaining increasing interest as green, sustainable, and biocompatible materials for the development of next-generation delivery vectors. The isolation of vesicles from complex plant matrix is a significant challenge considering the trade-off between yield and purity. Here, we used differential ultracentrifugation (dUC) for the bulk production of MVs and NVs from tomato (

Indexed as

biomanufacturingdifferential ultracentrifugationgradient ultracentrifugationnanovesiclesphospholipidsproteomicssize-exclusion chromatographySolanum lycopersicum L.tomato

Identifiers

PMID33322632
PMCPMC7764365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.