Evidence map›Paper›PMID 33322581›Full record

ArticlePathogens (Basel, Switzerland)2020

Lack of Interleukin-6 Affects IFN-γ and TNF-α Production and Early In Vivo Control of

Erika S Guimarães, Jéssica M Martins, Marco Túlio R Gomes, Daiane M Cerqueira, Sergio C Oliveira

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. ZBP1 sensesFrontiers in immunology · 2024
    Article
  5. Article
  6. Article
  7. Protective Effects againstJournal of microbiology and biotechnology · 2023
    Article
  8. Review
  9. Review
  10. Inflammatory Mechanism ofInternational journal of molecular sciences · 2022
    Review
  11. Immunostimulatory Effect of Postbiotics Prepared fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  12. Kinetics of Placental Infection by Different SmoothPathogens (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Epitope-Based Vaccine of aFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Erika S GuimarãesDepartment of Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Jéssica M MartinsDepartment of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Marco Túlio R GomesDepartment of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Daiane M CerqueiraDepartment of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-8051-3396
Sergio C OliveiraDepartment of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Universidade Federal de Minas Gerais · BR

Funding

Brucella survival strategy requires endoplasmic reticulum restructuring and interferes with innate immunityR01AI116453 · NIAID · FOUNDATION FOR RESEARCH DEVELOPMENT · PI BARBER, GLEN N, OLIVEIRA, SERGIO C · 2016 to 2025
$1.4M
CNPq 302660/2015-1 and 406883/2018-1FAPEMIG APQ-01945-17 and Rede 00140-16NIH HHS R01 AI116453
6 · The paper itself

Abstract

Interleukin-6 (IL-6) is a pleiotropic cytokine promptly produced in response to infections, which contributes to host defense through the stimulation of acute phase immune responses.

Indexed as

Brucella abortuscell recruitmentIL-6innate immunityneutrophils

Identifiers

PMID33322581
PMCPMC7764695
OpenAlexW3111029819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.