Evidence map›Paper›PMID 33322440›Full record

ArticleJournal of clinical medicine2020

Asthma-Like Features and Anti-Asthmatic Drug Prescription in Children with Non-CF Bronchiectasis.

Konstantinos Douros, Olympia Sardeli, Spyridon Prountzos, Angeliki Galani, Dafni Moriki, Efthymia Alexopoulou, Kostas N Priftis

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Konstantinos DourosAllergology and Pulmonology Unit, 3rd Paediatric Department, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Olympia SardeliAllergology and Pulmonology Unit, 3rd Paediatric Department, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0001-9913-1761
Spyridon Prountzos2nd Radiology Department, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.ORCID 0000-0001-9651-8338
Angeliki GalaniAllergology and Pulmonology Unit, 3rd Paediatric Department, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Dafni MorikiAllergology and Pulmonology Unit, 3rd Paediatric Department, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Efthymia Alexopoulou2nd Radiology Department, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.ORCID 0000-0001-8466-4127
Kostas N PriftisAllergology and Pulmonology Unit, 3rd Paediatric Department, National and Kapodistrian University of Athens, 12462 Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiectasis and asthma may share some characteristics and some patients may have both conditions. The present study aimed to examine the rationale of prophylactic inhaled corticosteroids (ICS) prescription in children with bronchiectasis. Data of children with radiologically established bronchiectasis were retrospectively reviewed. Episodes of dyspnea and wheezing, spirometric indices, total serum IgE, blood eosinophil counts, sensitization to aeroallergens, and air-trapping on expiratory CT scans, were recorded. The study included 65 children 1.5-16 years old, with non-CF bronchiectasis. Episodes of dyspnea or wheezing were reported by 22 (33.8%) and 23 (35.4%), respectively. Skin prick tests to aeroallergens (SPTs) were positive in 15 (23.0%) patients. Mosaic pattern on CT scans was observed in 37 (56.9%) patients. Dyspnea, presence of mosaic pattern, positive reversibility test, and positive SPTs were significantly correlated with the prescription of ICS. The prescription of ICS in children with bronchiectasis is more likely when there are certain asthma-like characteristics. The difficulty to set the diagnosis of real asthma in cases of bronchiectasis may justify the decision of clinicians to start an empirical trial with ICS in certain cases.

Indexed as

asthmachildreninhaled corticosteroidsnon-CF bronchiectasis

Identifiers

PMID33322440
PMCPMC7764222
OpenAlexW3111195055

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.