Evidence map›Paper›PMID 33322258›Full record

ArticleCancers2020

Expression of Extracellular Matrix-Related Genes and Their Regulatory microRNAs in Problematic Colorectal Polyps.

Margareta Žlajpah, Emanuela Boštjančič, Bojan Tepeš, Nina Zidar

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Margareta ŽlajpahFaculty of Medicine, Institute of Pathology, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-0937-3845
Emanuela BoštjančičFaculty of Medicine, Institute of Pathology, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-8091-4595
Bojan TepešGastroenterology Unit, AM DC Rogaška, 3250 Rogaška Slatina, Slovenia.
Nina ZidarFaculty of Medicine, Institute of Pathology, University of Ljubljana, 1000 Ljubljana, Slovenia.
University of Ljubljana · SIRogaška Medical Centre · SI

Funding

Slovenian research agency J3-1754Slovenian research agency P3-0054
6 · The paper itself

Abstract

Colorectal carcinoma usually evolves gradually, forming a spectrum of lesions, due to accumulation of genetic mutations and epigenetic alterations. Many early lesions are detected since the introduction of screening programs. The greatest challenge is to distinguish between adenomas with epithelial misplacement (AEM) and adenomas with early carcinoma (AEC), considering the diagnosis affects prognosis and treatment. We analyzed the expression of selected extracellular matrix (ECM)-related genes and proteins, and their regulatory microRNAs using RT-qPCR and immunohistochemistry in biopsies from 44 patients. Differences were observed in AEM in comparison to AEC for

Indexed as

adenoma with early carcinomaadenoma with epithelial misplacementcolorectal carcinomaextracellular matrix

Identifiers

PMID33322258
PMCPMC7764749
OpenAlexW3111749166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.