Evidence map›Paper›PMID 33322201›Full record

ArticleMolecules (Basel, Switzerland)2020

Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms.

A F M Motiur Rahman, Wencui Yin, Adnan A Kadi, Yurngdong Jahng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

A F M Motiur RahmanDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-5807-5625
Wencui YinDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Adnan A KadiDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-8115-4228
Yurngdong JahngCollege of Pharmacy, Yeungnam University, Gyeongsan 38541, Korea.
King Saud University · SAYeungnam University · KR

Funding

National Plan for Science, Technology and Innovation 12-MED-2439-02
6 · The paper itself

Abstract

Galeon, a natural cyclic-diarylheptanoid (CDH), which was first isolated from

Indexed as

Molecular Docking SimulationMolecular Dynamics SimulationAnimalsBinding SitesCyclophanesCytochrome P-450 Enzyme SystemDiarylheptanoidsIsoenzymesMicrosomes, LiverMolecular ConformationMolecular StructureProtein BindingRatsStructure-Activity RelationshipCyclophanesCytochrome P-450 Enzyme SystemDiarylheptanoidsgaleonIsoenzymescyclic-diarylheptanoidgaleongaleon conjugatesgaleon-CYP450 interactionsgaleon metabolites

Identifiers

PMID33322201
PMCPMC7763192
OpenAlexW3112706318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.