Evidence map›Paper›PMID 33322196›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Powerful Antibacterial Peptides from Egg Albumin Hydrolysates.

Abdul-Raouf Al-Mohammadi, Ali Osman, Gamal Enan, Seham Abdel-Shafi, Mona El-Nemer, Mahmoud Sitohy, Mohamed A Taha

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  11. The Association betweenAntibiotics (Basel, Switzerland) · 2022
    Article
  12. Silver-Protein Nanocomposites as Antimicrobial Agents.Nanomaterials (Basel, Switzerland) · 2021
    Article
  13. Assessment the using of silica nanoparticles (SiOSaudi journal of biological sciences · 2021
    Article
  14. Article
  15. Article
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  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdul-Raouf Al-MohammadiDepartment of Science, King Khalid Military Academy, P.O. Box 22140, Riyadh 11495, Saudi Arabia.
Ali OsmanBiochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0001-7174-0207
Gamal EnanBotany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0001-7794-784X
Seham Abdel-ShafiBotany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.ORCID 0000-0002-8311-7946
Mona El-NemerBotany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Mahmoud SitohyBiochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0001-6623-4860
Mohamed A TahaBotany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Native egg albumin (NEA) was isolated from hen eggs and hydrolyzed by pepsin to produce hydrolyzed egg albumin (HEA). HEA was chemically characterized and screened for its antibacterial activity against 10 pathogenic bacteria (6 Gram (+) and 4 Gram (-)). The SDS-PAGE pattern of NEA showed molecular weights of hen egg albumin subunits ranging from 30 to 180 kDa. The highest intensive bands appeared at a molecular mass of about 50 and 97 kDa. Ultra-performance liquid chromatography (UPLC) of the peptic HEA revealed 44 peptides, 17 of them were dipeptides, and the other 27 fractions corresponded to bigger peptides (3-9 amino acids). The dipeptides and big peptides represented 26% and 74% of the total hydrolysate, respectively. The MIC of HEA was about 100 μg/L for

Indexed as

acute toxicityantibacterial activityegg albuminhydrolysispathogenic bacteriapepsin

Identifiers

PMID33322196
PMCPMC7763489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.