Evidence map›Paper›PMID 33322145›Full record

ReviewCells2020

Role of Aquaporins in the Physiological Functions of Mesenchymal Stem Cells.

Antonella Zannetti, Gheorghe Benga, Arturo Brunetti, Francesco Napolitano, Luigi Avallone, Alessandra Pelagalli

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. The Role of Aquaporins in Epileptogenesis-A Systematic Review.International journal of molecular sciences · 2023
    Pooled it
  2. Article
  3. Impact of aging on CD146Frontiers in bioengineering and biotechnology · 2026
    Article
  4. Review
  5. Article
  6. Genome-Wide Analysis of Aquaporins Gene Family inInternational journal of molecular sciences · 2024
    Article
  7. Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury.International journal of molecular sciences · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. The multifaceted role of aquaporins in physiological cell migration.American journal of physiology. Cell physiology · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Chicken Mesenchymal Stem Cells and Their Applications: A Mini Review.Animals : an open access journal from MDPI · 2021
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Antonella ZannettiInstitute of Biostructure and Bioimaging, CNR, Via T. De Amicis 95, 80145 Naples, Italy.ORCID 0000-0002-6753-3659
Gheorghe BengaRomanian Academy, Cluj-Napoca Branch, Strada Republicii 9, 400015 Cluj-Napoca, Romania.
Arturo BrunettiDepartment of Advanced Biomedical Sciences, University of Naples Federico II, via Pansini 5, 80131 Naples, Italy.
Francesco NapolitanoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, via Veterinaria 1, 80137 Naples, Italy.ORCID 0000-0003-0884-1851
Luigi AvalloneDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, via Veterinaria 1, 80137 Naples, Italy.
Alessandra PelagalliInstitute of Biostructure and Bioimaging, CNR, Via T. De Amicis 95, 80145 Naples, Italy.ORCID 0000-0002-1133-4300
Institute of Biostructure and Bioimaging · ITUniversity of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITRomanian Academy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaporins (AQPs) are a family of membrane water channel proteins that control osmotically-driven water transport across cell membranes. Recent studies have focused on the assessment of fluid flux regulation in relation to the biological processes that maintain mesenchymal stem cell (MSC) physiology. In particular, AQPs seem to regulate MSC proliferation through rapid regulation of the cell volume. Furthermore, several reports have shown that AQPs play a crucial role in modulating MSC attachment to the extracellular matrix, their spread, and migration. Shedding light on how AQPs are able to regulate MSC physiological functions can increase our knowledge of their biological behaviours and improve their application in regenerative and reparative medicine.

Indexed as

AquaporinsBiological TransportBrainCell DifferentiationCell Membrane PermeabilityCell MovementHumansMesenchymal Stem CellsProtein IsoformsRegenerative MedicineAquaporinsProtein Isoformsaquaporinscell differentiationcell migrationmesenchymal stem cellsphysiologywater channel

Identifiers

PMID33322145
PMCPMC7763964
OpenAlexW3113182222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.