Evidence map›Paper›PMID 33322098›Full record

ArticleInternational journal of molecular sciences2020

Interferon Beta Activity Is Modulated via Binding of Specific S100 Proteins.

Alexey S Kazakov, Alexander D Sofin, Nadezhda V Avkhacheva, Alexander I Denesyuk, Evgenia I Deryusheva, Victoria A Rastrygina, Andrey S Sokolov, Maria E Permyakova, Ekaterina A Litus, Vladimir N Uversky and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. S100A6 Protein-Expression and Function in Norm and Pathology.International journal of molecular sciences · 2023
    Review
  7. Specific S100 Proteins Bind Tumor Necrosis Factor and Inhibit Its Activity.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Interferon-β Activity Is Affected by S100B Protein.International journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Mechanism of ZnBiomolecules · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Alexey S KazakovInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Alexander D SofinInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Nadezhda V AvkhachevaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Alexander I DenesyukInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.ORCID 0000-0002-5461-2294
Evgenia I DeryushevaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Victoria A RastryginaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.ORCID 0000-0001-8801-3786
Andrey S SokolovInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Maria E PermyakovaInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Ekaterina A LitusInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Vladimir N UverskyInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.ORCID 0000-0002-4037-5857
Eugene A PermyakovInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.
Sergei E PermyakovInstitute for Biological Instrumentation, Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, Institutskaya str., 7, 142290 Pushchino, Russia.ORCID 0000-0003-4086-3137
Institute for Biological Instrumentation · RUÅbo Akademi University · FIUniversity of South Florida · US

Funding

Joe, Pentti, and Tor Borg Memorial Fund N/ARussian Science Foundation №19-14-00289Sigrid Jusélius Foundation N/A
6 · The paper itself

Abstract

Interferon-β (IFN-β) is a pleiotropic cytokine used for therapy of multiple sclerosis, which is also effective in suppression of viral and bacterial infections and cancer. Recently, we reported a highly specific interaction between IFN-β and S100P lowering IFN-β cytotoxicity to cancer cells (Int J Biol Macromol. 2020; 143: 633-639). S100P is a member of large family of multifunctional Ca

Indexed as

Amino Acid SequenceCalciumCalcium-Binding ProteinsCardiovascular DiseasesCell Cycle ProteinsCell SurvivalDimerizationHumansInterferon-betaKineticsMCF-7 CellsModels, ChemicalMolecular Docking SimulationNeoplasm ProteinsNeoplasmsNervous System DiseasesCalciumCalcium-Binding ProteinsCell Cycle ProteinsInterferon-betaNeoplasm ProteinsS100A1 proteinS100A4 protein, humanS100A6 protein, humanS100 Calcium-Binding Protein A4S100 Calcium Binding Protein A6S100P protein, humanS100 Proteinscancercytokineinterferonprotein–protein interactionS100 protein

Identifiers

PMID33322098
PMCPMC7764042
OpenAlexW3113148540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.