ReviewChildren (Basel, Switzerland)2020
Difficult and Severe Asthma in Children.
Review in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Implementation of Coach McLungsBMC medical informatics and decision making · 2022Trial
- <italic>TXK</italic> Functional Variants Contribute to Asthma by Regulating Th1 and Th17 Cytokine Pathways.International archives of allergy and immunology · 2025Article
- Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma.Current allergy and asthma reports · 2023Review
- T2-Low Asthma: A Discussed but Still Orphan Disease.Biomedicines · 2023Review
- Editorial: Difficult and severe asthma in children, volume II.Frontiers in pediatrics · 2023Article
- Characteristics of Allergic, Eosinophilic, and Overlapping Asthma Phenotypes Among Pediatric Patients with Current Asthma: A Cross-Sectional Study from Saudi Arabia.Journal of asthma and allergy · 2023Article
- Respiratory Symptoms, Allergies, and Environmental Exposures in Children with and without Asthma.International journal of environmental research and public health · 2022Article
- Association of mold levels in urban children's homes with difficult-to-control asthma.The Journal of allergy and clinical immunology · 2022Article
- Update on Long-Acting Anticholinergics in Children and Adolescents With Difficult and Severe Asthma.Frontiers in pediatrics · 2022Review
- Editorial: Insights in pediatric pulmonology 2021.Frontiers in pediatrics · 2022Article
- Severe Pediatric Asthma Therapy: Mepolizumab.Frontiers in pediatrics · 2022Review
- Progress in diagnosis and treatment of difficult-to-treat asthma in children.Therapeutic advances in respiratory diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is the most frequent chronic inflammatory disease of the lower airways affecting children, and it can still be considered a challenge for pediatricians. Although most asthmatic patients are symptom-free with standard treatments, a small percentage of them suffer from uncontrolled persistent asthma. In these children, a multidisciplinary systematic assessment, including comorbidities, treatment-related issues, environmental exposures, and psychosocial factors is needed. The identification of modifiable factors is important to differentiate children with difficult asthma from those with true severe therapy-resistant asthma. Early intervention on modifiable factors for children with difficult asthma allows for better control of asthma without the need for invasive investigation and further escalation of treatment. Otherwise, addressing a correct diagnosis of true severe therapy-resistant asthma avoids diagnostic and therapeutic delays, allowing patients to benefit from using new and advanced biological therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.