ReviewInternational journal of environmental research and public health2020
Wastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: A Valuable Tool for COVID-19 Surveillance-A Brief Review.
Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.
- Wastewater surveillance to infer COVID-19 transmission: A systematic review.The Science of the total environment · 2022Pooled it
- Toward a quality-managed operational architecture for wastewater surveillance of zoonotic and emerging pathogens.Applied and environmental microbiology · 2026Review
- Article
- Detection, persistence, and rising prevalence of oncogenic viruses revealed by wastewater metagenomics.Applied and environmental microbiology · 2026Article
- High Detection Frequency of Enteric Pathogens: Insight from Wastewater-Based Epidemiology (WBE) Surveillance Approach in Dakar, Senegal.International journal of environmental research and public health · 2026Article
- Wastewater-based epidemiology reveals spatiotemporal dynamics and diurnal temperature range effects on post-pandemic SARS-CoV-2 infection burden in Chongqing, China.Frontiers in public health · 2026Article
- Advancing health equity in wastewater-based epidemiology: A global critical review and conceptual framework.SSM - population health · 2025Review
- Hotspots and Trends in Research on Early Warning of Infectious Diseases: A Bibliometric Analysis Using CiteSpace.Healthcare (Basel, Switzerland) · 2025Article
- Thermally Responsive Alkane Partitions and a Magnetofluidic Assay for Point-of-Sample Detection of Viruses in Wastewater.Biosensors · 2025Article
- Can Wastewater Surveillance Enhance Genomic Tracking of Climate-Driven Pathogens?Microorganisms · 2025Review
- Tracking SARS-CoV-2 and its variants in wastewater in Tunisia.Journal of water and health · 2024Article
- Review
- Analytical validation of a semi-automated methodology for quantitative measurement of SARS-CoV-2 RNA in wastewater collected in northern New England.Microbiology spectrum · 2024Article
- Fate-and-transport modeling of SARS-CoV-2 for rural wastewater-based epidemiology application benefit.Heliyon · 2024Article
- Changes to Public Health Surveillance Methods Due to the COVID-19 Pandemic: Scoping Review.JMIR public health and surveillance · 2024Article
- Molecular Characterization of Gastroenteric Viruses in Wastewater from Cities in Uruguay.Food and environmental virology · 2023Article
- Diurnal changes in pathogenic and indicator virus concentrations in wastewater.Environmental science and pollution research international · 2023Article
- SARS-CoV-2 detection and inactivation in water and wastewater: review on analytical methods, limitations and future research recommendations.Emerging microbes & infections · 2023Review
- Environmental sampling for typhoidal Salmonellas in household and surface waters in Nepal identifies potential transmission pathways.PLoS neglected tropical diseases · 2023Article
- The Chelsea Project: Turning Research and Wastewater Surveillance on COVID-19 Into Health Equity Action, Massachusetts, 2020-2021.American journal of public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
SARS-CoV-2 is the causative agent of the current COVID-19 pandemic. Disease clinical manifestations range from asymptomatic to severe multiple organ damage. SARS-CoV-2 uses ACE2 as a cellular receptor, which is abundantly expressed in the small intestine, allowing viral replication in the gastrointestinal tract. Viral RNA has been detected in the stool of COVID-19 patients and viable viruses had been isolated in some of these samples. Thus, a putative role of SARS-CoV-2 fecal-oral transmission has been argued. SARS-CoV-2 is shed in human excreta and further disposed in the sewerage or in the environment, in poor basic sanitation settings. Wastewater-based epidemiology (WBE) is a valuable population level approach for monitoring viral pathogens and has been successfully used in different contexts. This review summarizes the current global experience on SARS-CoV-2 WBE in distinct continents and viral detection in polluted surface water. The advantages and concerns of this strategy for SARS-CoV-2 surveillance are discussed. Outcomes suggest that WBE is a valuable early warning alert and a helpful complementary surveillance tool to subside public health response, to tailor containment and mitigation measures and to determine target populations for testing. In poor sanitation settings, contaminated rivers could be alternatively used as a source for environmental surveillance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.