ArticleBrain sciences2020
Age-Related Decline of Sensorimotor Integration Influences Resting-State Functional Brain Connectivity.
Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Relating Cognition to both Brain Structure and Function: A Systematic Review of Methods.Brain connectivity · 2023Pooled it
- Early sleep after action observation plus motor imagery improves gait and balance abilities in older adults.Scientific reports · 2024Trial
- The dynamic bodily self across lifespan: Agency, ownership, and the plasticity of internal body models.Psychonomic bulletin & review · 2026Review
- Article
- Speech as a dynamic biomarker of physical aging: a longitudinal study.GeroScience · 2026Article
- Effects of a 3D motion recognition-based virtual training system on balance and gait performance in older adults.Physical activity and nutrition · 2026Article
- Age-related changes to brain energetics revealed by PET/MRI imaging.NeuroImage. Clinical · 2026Article
- Distinct roles of brain network flexibility in motor learning across age.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Supplementation of aged garlic extract attenuates age-associated memory impairment and cognitive decline: Involvement of molecular pathways in the cortex and hippocampus.Biomedical reports · 2026Article
- [Research on the relationship between resting-state spontaneous electroencephalography and task-evoked electroencephalography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Review
- Investigating age-related decline in sensorimotor control using robotic tasks.Frontiers in aging neuroscience · 2025Article
- Cortical excitability and the aging brain: toward a biomarker of cognitive resilience.Frontiers in psychology · 2025Article
- Decline in Sensory Integration in Old Age and Its Related Functional Brain Connectivity Correlates Observed during a Virtual Reality Task.Brain sciences · 2024Article
- Development of the Sensory-Motor Dysfunction Questionnaire and Pilot Reliability Testing.Brain sciences · 2024Article
- Stimulated cervical afferent input increases postural instability in older people with chronic neck pain: a cross-sectional study.BMC geriatrics · 2024Article
- Brain-wide functional connectome analysis of 40,000 individuals reveals brain networks that show aging effects in older adults.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Perceptual Integration Compensates for Attention Deficit in Elderly during Repetitive Auditory-Based Sensorimotor Task.Sensors (Basel, Switzerland) · 2023Article
- Education differentiates cognitive performance and resting state fMRI connectivity in healthy aging.Frontiers in aging neuroscience · 2023Article
- Normal aging in mice is associated with a global reduction in cortical spectral power and network-specific declines in functional connectivity.NeuroImage · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Age-related decline in sensorimotor integration involves both peripheral and central components related to proprioception and kinesthesia. To explore the role of cortical motor networks, we investigated the association between resting-state functional connectivity and a gap-detection angle measured during an arm-reaching task. Four region pairs, namely the left primary sensory area with the left primary motor area (S1left-M1left), the left supplementary motor area with M1left (SMAleft-M1left), the left pre-supplementary motor area with SMAleft (preSMAleft-SMAleft), and the right pre-supplementary motor area with the right premotor area (preSMAright-PMdright), showed significant age-by-gap detection ability interactions in connectivity in the form of opposite-sign correlations with gap detection ability between younger and older participants. Morphometry and tractography analyses did not reveal corresponding structural effects. These results suggest that the impact of aging on sensorimotor integration at the cortical level may be tracked by resting-state brain activity and is primarily functional, rather than structural. From the observation of opposite-sign correlations, we hypothesize that in aging, a "low-level" motor system may hyper-engage unsuccessfully, its dysfunction possibly being compensated by a "high-level" motor system, wherein stronger connectivity predicts higher gap-detection performance. This hypothesis should be tested in future neuroimaging and clinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.