ArticleMolecules (Basel, Switzerland)2020
Breath Analysis: Comparison among Methodological Approaches for Breath Sampling.
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The trial behind it
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Who cites it
31 citing papers in PubMed, 80 citations in OpenAlex.
- Comprehensive Two-Dimensional Gas Chromatography-Mass Spectrometry Analysis of Exhaled Breath Compounds after Whole Grain Diets.Molecules (Basel, Switzerland) · 2021Trial
- Exhaled Breath Analysis for Detection of Interstitial Lung Diseases Using Real-Time PTR-TOF-MS.International journal of molecular sciences · 2026Article
- Respirator-integrated continuous gas sampling for broadband optical spectroscopy.Scientific reports · 2026Article
- Soft ionization by chemical reaction in transfer-high-resolution mass spectrometry for clinical exhaled breath profiling.Analytical and bioanalytical chemistry · 2026Article
- Investigation of sputum volatiles to classify active tuberculosis: A pilot study.Tuberculosis (Edinburgh, Scotland) · 2026Article
- AI-driven breath biopsy from a case-control study assists in the early detection of paediatric brain tumours.EBioMedicine · 2025Article
- Volatile Organic Compounds (VOCs) in Neurodegenerative Diseases (NDDs): Diagnostic Potential and Analytical Approaches.Molecules (Basel, Switzerland) · 2025Review
- Exhaled Aldehydes and Ketones as Biomarkers of Lung Cancer and Diabetes: Review of Sensor Technologies for Early Disease Diagnosis.Biosensors · 2025Review
- The Role of Breath Analysis in the Non-Invasive Early Diagnosis of Malignant Pleural Mesothelioma (MPM) and the Management of At-Risk Individuals.Molecules (Basel, Switzerland) · 2025Observational
- Parallel Offline Breath Sampling for Cross-Validated Analysis of Volatile Organic Compound Metabolites.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Systematic comparison of methods for offline breath sampling.Analytical and bioanalytical chemistry · 2025Article
- Breathomics: A Non-Invasive Approach for the Diagnosis of Breast Cancer.Bioengineering (Basel, Switzerland) · 2025Review
- Breath Analysis: Identification of Potential Volatile Biomarkers for Non-Invasive Diagnosis of Chronic Kidney Disease (CKD).Molecules (Basel, Switzerland) · 2024Observational
- High-quality identification of volatile organic compounds (VOCs) originating from breath.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Sample Collection and Processing in Volatile Organic Compound Analysis for Gastrointestinal Cancers.Diagnostics (Basel, Switzerland) · 2024Review
- Progress and challenges of developing volatile metabolites from exhaled breath as a biomarker platform.Metabolomics : Official journal of the Metabolomic Society · 2024Review
- Unraveling the microbiome-metabolome nexus: a comprehensive study protocol for personalized management of Behçet's disease using explainable artificial intelligence.Frontiers in microbiology · 2024Article
- Breathomics Detect the Cardiovascular Disease: Delusion or Dilution of the Metabolomic Signature.Current cardiology reviews · 2024Review
- Pioneering noninvasive colorectal cancer detection with an AI-enhanced breath volatilomics platform.Theranostics · 2024Article
- Development of a new breath collection method for analyzing volatile organic compounds from intubated mouse models.Biology methods & protocols · 2024Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite promising results obtained in the early diagnosis of several pathologies, breath analysis still remains an unused technique in clinical practice due to the lack of breath sampling standardized procedures able to guarantee a good repeatability and comparability of results. The most diffuse on an international scale breath sampling method uses polymeric bags, but, recently, devices named Mistral and ReCIVA, able to directly concentrate volatile organic compounds (VOCs) onto sorbent tubes, have been developed and launched on the market. In order to explore performances of these new automatic devices with respect to sampling in the polymeric bag and to study the differences in VOCs profile when whole or alveolar breath is collected and when pulmonary wash out with clean air is done, a tailored experimental design was developed. Three different breath sampling approaches were compared: (a) whole breath sampling by means of Tedlar bags, (b) the end-tidal breath collection using the Mistral sampler, and (c) the simultaneous collection of the whole and alveolar breath by using the ReCIVA. The obtained results showed that alveolar fraction of breath was relatively less affected by ambient air (AA) contaminants (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.