Evidence map›Paper›PMID 33321725›Full record

ArticleJournal of personalized medicine2020

Pulmonary Manifestations of Plasma Cell Type Idiopathic Multicentric Castleman Disease: A Clinicopathological Study in Comparison with IgG4-Related Disease.

Midori Filiz Nishimura, Takuro Igawa, Yuka Gion, Sakura Tomita, Dai Inoue, Akira Izumozaki, Yoshifumi Ubara, Yoshito Nishimura, Tadashi Yoshino, Yasuharu Sato

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Castleman's disease in the rheumatological practice.Zeitschrift fur Rheumatologie · 2024
    Review
  5. Article
  6. [Castleman's disease in the rheumatological practice].Zeitschrift fur Rheumatologie · 2024
    Review
  7. Article
  8. Clinical characteristics of IgG4Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  9. Article
  10. Historical and pathological overview of Castleman disease.Journal of clinical and experimental hematopathology : JCEH · 2022
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Midori Filiz NishimuraDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.ORCID 0000-0002-8433-4870
Takuro IgawaDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Yuka GionDivision of Pathophysiology, Okayama University Graduate School of Health Sciences, Okayama 700-8558, Japan.
Sakura TomitaDepartment of Pathology, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
Dai InoueDepartment of Radiology, Kanazawa University Graduate School of Medical Sciences, Ishikawa 920-8641, Japan.
Akira IzumozakiDepartment of Radiology, Kanazawa University Graduate School of Medical Sciences, Ishikawa 920-8641, Japan.
Yoshifumi UbaraNephrology Center, Toranomon Hospital Kajigaya, Kanagawa 213-0015, Japan.
Yoshito NishimuraDepartment of General Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.ORCID 0000-0003-0224-7501
Tadashi YoshinoDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Yasuharu SatoDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.ORCID 0000-0001-5234-6861
Okayama University · JPKanazawa University · JPTokai University · JPToranomon Hospital · JP

Funding

Grant-in-Aid for Scientific Research JP 20K07407
6 · The paper itself

Abstract

Plasma cell type idiopathic multicentric Castleman disease (PC-iMCD) occasionally manifests as parenchymal lung disease. This study aimed to elucidate the detailed clinicopathological features of lung lesions in PC-iMCD and compare the findings with those in immunoglobulin (Ig) G4-related disease (IgG4-RD), the most difficult differential diagnosis of PC-iMCD. We analyzed the clinicopathological findings and immunohistochemical expression patterns of interleukin-6 (IL-6) and Igs in lung specimens from 16 patients with PC-iMCD and 7 patients with IgG4-RD. Histologically, pulmonary PC-iMCD could not be differentiated from IgG4-RD based on lesion distribution patterns, the number of lymphoid follicles and obliterative vasculitis, or fibrosis types. The eosinophil count was higher in the IgG4-RD group than in the PC-iMCD group (

Indexed as

hyper IL-6 syndromeIgG4-related diseaseIL-6immunohistochemistryplasma cell type idiopathic multicentric Castleman disease

Identifiers

PMID33321725
PMCPMC7768369
OpenAlexW3111742907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.