ReviewJournal of clinical medicine2020
Pars Plana Vitrectomy and the Risk of Ocular Hypertension and Glaucoma: Where Are We?
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- F4H5 Alleviates Increased Outflow Resistance Induced by Emulsified Silicone Oil In Vitro.Investigative ophthalmology & visual science · 2025Article
- A retrospective outcomes study 25-gauge 10,000 CPM beveled-tip and 25-gauge flat-tip microincision vitrectomy for proliferative diabetic retinopathy treatment.Frontiers in medicine · 2025Article
- Endothelial Cell Changes After Pars Plana Vitrectomy: A Cross-Sectional Study in a Tertiary Care Center.Cureus · 2024Article
- Increased late-onset glaucoma risk following vitrectomy for macular pucker or hole.Eye (London, England) · 2024Article
- Efficacy of Continuous-Wave Transscleral Cyclophotocoagulation Post-Pars Plana Vitrectomy in Glaucoma Patients: A Retrospective Study from Poland.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Combining Perfluorobutylpentane (FTurkish journal of ophthalmology · 2023Article
- Incidence of early complications requiring treatment plan changes after vitreoretinal surgery: a single-center study in South Korea.BMC ophthalmology · 2023Article
- The survival analysis and feasibility study of Pars Plana Vitrectomy (PPV) in the treatment of retinoblastoma.Journal of cancer research and clinical oncology · 2023Article
- Commentary: Glaucoma complicating vitreoretinal surgery!Indian journal of ophthalmology · 2023Article
- Evaluation of corneal hysteresis after pars plana vitrectomy combined phacoemulsification and intraocular lens implantation.Scientific reports · 2022Article
- Long-term outcome of supraciliary gold micro shunt in refractory glaucoma.Acta ophthalmologica · 2022Article
- Vitreous function and intervention of it with vitrectomy and other modalities.International journal of ophthalmology · 2022Article
- Case Report: Microincision Vitreous Surgery Induces Bleb Failure in Eyes With Functional Filtering Bleb.Frontiers in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose is to review the pathogenic mechanism for ocular hypertension and glaucoma development after pars plana vitrectomy. Both acute and chronic causes are considered, and special attention is paid to the theories and clinical evidence on the risk of developing Open Angle Glaucoma (OAG) after Pars Plana Vitrectomy (PPV). Most existing scientific literature on the issue agree on the role of ascorbate as an oxygen scavenger within the vitreous chamber. Oxygen tension in the vitreous and anterior chamber is maximum inn proximity of the retinal surface and endothelium, respectively and steeply decreases toward the lens, on both sides, and trabecular meshwork. Vitreous removal and, to a lesser extent, liquefaction, greatly reduces oxygen tension gradient in vitreous chamber while cataract extraction has similar effects on anterior chamber oxygen gradients. Oxygen derivatives originated from the cornea and retina are actively reduced by the vitreous gel and/or the crystalline lens. Vitreous removal and cataract extraction reduce drastically this function. Most reported clinical series confirm this hypothesis although protocol difference and follow-up length greatly impact the reliability of results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.