ArticleHealth & place2021
Neighborhood disadvantage is associated with stable deficits in neurocognitive functioning in traumatically-injured adults.
Article in Health & place, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Applications of Machine Learning for Cognitive Health in Older Individuals With HIV: Rapid Systematic Review.JMIR aging · 2025Pooled it
- Trial
- Neighborhood Deprivation and Adolescent Mental Health: The Protective Role of School Staffing Patterns.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors.Translational psychiatry · 2026Article
- Cross-sectional analysis of neighbourhood profiles and mental health conditions in the USA: insights from the All of Us Research Program.BMJ public health · 2026Article
- Associations of neighborhood threat and deprivation with psychopathology: Uncovering neural mechanisms.Development and psychopathology · 2025Article
- Neural processes of emotional conflict detection and prediction of posttraumatic stress disorder symptom clusters in traumatic injury survivors.Psychological trauma : theory, research, practice and policy · 2025Article
- Understanding Onset, Dynamic Transitions, and Associated Inequality Risk Factors for Adverse Posttraumatic Neuropsychiatric Sequelae After Trauma Exposure.Psychiatric research and clinical practice · 2025Article
- Evaluating Social Determinants of Health-Based Alternatives to Race-Based Cognitive Normative Models.Neurology · 2024Article
- Experiences of racial discrimination and adverse gene expression among black individuals in a level 1 trauma center sample.Brain, behavior, and immunity · 2024Article
- Attributional negativity bias and acute stress disorder symptoms mediate the association between trauma history and future posttraumatic stress disorder.Journal of traumatic stress · 2023Article
- Association of Neighborhood Deprivation With Cognitive and Mood Outcomes in Adults With Pharmacoresistant Temporal Lobe Epilepsy.Neurology · 2023Article
- Machine learning prediction of posttraumatic stress disorder trajectories following traumatic injury: Identification and validation in two independent samples.Journal of traumatic stress · 2022Article
- Event centrality and posttraumatic stress symptoms after traumatic injury: A longitudinal investigation.Journal of traumatic stress · 2022Article
- Neighborhood Socioeconomic Disadvantage and the Neurobiology of Uncertainty in Traumatically Injured Adults.Biological psychiatry global open science · 2022Article
- Neighborhood Disadvantage Associated With Blunted Amygdala Reactivity to Predictable and Unpredictable Threat in a Community Sample of Youth.Biological psychiatry global open science · 2022Article
- Neural impact of neighborhood socioeconomic disadvantage in traumatically injured adults.Neurobiology of stress · 2021Article
- Racial Discrimination is Associated with Acute Posttraumatic Stress Symptoms and Predicts Future Posttraumatic Stress Disorder Symptom Severity in Trauma-Exposed Black Adults in the United States.Journal of traumatic stress · 2021Article
- Acute White Matter Integrity Post-trauma and Prospective Posttraumatic Stress Disorder Symptoms.Frontiers in human neuroscience · 2021Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundIn trauma-exposed adults, the relationship between an individual's socioeconomic position (SEP) and post-traumatic stress disorder (PTSD) has been well demonstrated. One potential mechanism by which the stress associated with lower SEPs may impact trauma outcomes is through changes in neurocognition. In both healthy and clinical samples, area-level factors also appear to be independently related to neurocognition. Far less is known about how neighborhood socioeconomic disadvantage, may impact cognition in traumatically-injured adults. The current study employed hierarchical linear modeling to longitudinally investigate whether neighborhood disadvantage was associated with neurocognitive functioning in five domains: processing speed, sustained attention, controlled attention, cognitive flexibility, and response inhibition.
methodsOne-hundred and ninety-five socioeconomically diverse traumatically-injured subjects (mean age = 32.8, 52.8% female) were recruited from an Emergency Department. Two-weeks, three-months, and six-months post-trauma, participants completed self-report measures and a computerized test battery to evaluate neurocognition. An Area Deprivation Index (ADI) score, a measure of a neighborhood's socioeconomic disadvantage, was derived from each participants' home address.
resultsGreater neighborhood disadvantage was significantly related to lower scores in all domains. Results of hierarchical linear models revealed neighborhood disadvantage was significantly associated with processing speed, controlled attention, cognitive flexibility, and response inhibition across time, even after adjusting for individual annual household income, baseline PTSD symptoms, and previous adverse life experiences. This relationship was stable for all domains except sustained attention, which varied across time.
conclusionThese findings indicate neighborhood disadvantage contributes uniquely to neurocognitive functioning and, for the majority of domains, these contributions are stable across time. The relationship between area-level variables and cognitive function may underlie individual vulnerability to developing psychiatric disorders. Future work should continue to examine the interaction between socioenvironmental stressors and PTSD symptoms longitudinally.
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