Evidence map›Paper›PMID 33320988›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Light-Responsive Dynamic DNA-Origami-Based Plasmonic Assemblies.

Joonas Ryssy, Ashwin K Natarajan, Jinhua Wang, Arttu J Lehtonen, Minh-Kha Nguyen, Rafal Klajn, Anton Kuzyk

Erratum issuedAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. pH-Driven Actuation of Unmodified DNA Origami Rectangles.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Transient Activation Windows Program Adaptive Photochemical Responses.Angewandte Chemie (International ed. in English) · 2026
    Article
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  5. Review
  6. DNA Origami and Its Applications in Synthetic Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Controlling DNA nanodevices with light-switchable buffers.Chemical communications (Cambridge, England) · 2023
    Article
  16. Article
  17. Review
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Joonas RyssyDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, 00076, Aalto, Finland.ORCID 0000-0001-9894-5050
Ashwin K NatarajanDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, 00076, Aalto, Finland.ORCID 0000-0001-7897-708X
Jinhua WangDepartment of Organic Chemistry, Weizmann Institute of Science, Rehovot, 76100, Israel.
Arttu J LehtonenDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, 00076, Aalto, Finland.ORCID 0000-0001-9435-136X
Minh-Kha NguyenDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, 00076, Aalto, Finland.ORCID 0000-0003-3456-3162
Rafal KlajnDepartment of Organic Chemistry, Weizmann Institute of Science, Rehovot, 76100, Israel.ORCID 0000-0002-6320-8875
Anton KuzykDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, 00076, Aalto, Finland.ORCID 0000-0001-8060-6122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA nanotechnology offers a versatile toolbox for precise spatial and temporal manipulation of matter on the nanoscale. However, rendering DNA-based systems responsive to light has remained challenging. Herein, we describe the remote manipulation of native (non-photoresponsive) chiral plasmonic molecules (CPMs) using light. Our strategy is based on the use of a photoresponsive medium comprising a merocyanine-based photoacid. Upon exposure to visible light, the medium decreases its pH, inducing the formation of DNA triplex links, leading to a spatial reconfiguration of the CPMs. The process can be reversed simply by turning the light off and it can be repeated for multiple cycles. The degree of the overall chirality change in an ensemble of CPMs depends on the CPM fraction undergoing reconfiguration, which, remarkably, depends on and can be tuned by the intensity of incident light. Such a dynamic, remotely controlled system could aid in further advancing DNA-based devices and nanomaterials.

Indexed as

chiral plasmonicsDNA origamiphotoacidself-assemblystimuli-responsive materials

Identifiers

PMID33320988
PMCPMC7986157

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.