Evidence map›Paper›PMID 33320799›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.

Wei Li, Lu Long, Xudong Yang, Zhen Tong, Mark Southwood, Ross King, Paola Caruso, Paul D Upton, Peiran Yang, Geoffrey A Bocobo and 13 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
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  5. <p>Cigarette smoke combined withMolecular medicine reports · 2026
    Article
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  8. Review
  9. Article
  10. Acute lung injury: pathogenesis and treatment.Journal of translational medicine · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 3 countries.

Wei LiDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Lu LongDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Xudong YangDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Zhen TongDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Mark SouthwoodDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Ross KingWilliam Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Paola CarusoDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Paul D UptonDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Peiran YangCardiovascular Medicine Division and.
Geoffrey A BocoboCardiovascular Medicine Division and.
Ivana NikolicCardiovascular Medicine Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Angelica HigueraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Richard M SalmonDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
He JiangDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Katharine M LodgeNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Kim HoenderdosDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Rebecca M BaronDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital-Harvard Medical School, Harvard University, Boston, Massachusetts.
Paul B YuCardiovascular Medicine Division and.
Alison M CondliffeDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
Charlotte SummersDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Sussan NoursharghWilliam Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Edwin R ChilversNational Heart and Lung Institute, Imperial College London, London, United Kingdom; and.
Nicholas W MorrellDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBBrigham and Women's Hospital · USImperial College London · GBQueen Mary University of London · GBMassachusetts General Hospital · USUniversity of Sheffield · GB

Funding

Mesenchymal Stromal Cell Conditioning by Carbon MonoxideP01HL108801 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHOI, AUGUSTINE M · 2011 to 2015
$13.8M
Therapeutic modulation of zinc for lung injury and mechanobiologyR01HL142093 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BARON, REBECCA M, TSCHUMPERLIN, DANIEL J. · 2019 to 2022
$2.8M
Context-specific angiogenic signaling in the pulmonary vasculatureR01HL159443 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI YU, PAUL B · 2021 to 2024
$2.4M
HLS- Cyclic CAR peptide: a targeted therapy for pulmonary hypertensionR42HL132742 · NHLBI · VASCULAR BIOSCIENCES · PI YU, PAUL B · 2017 to 2019
$2.3M
Molecular imaging of angiogenic activity in pulmonary arterial hypertensionR01HL131910 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI YU, PAUL B · 2016 to 2018
$2.3M
British Heart Foundation FS/18/40/33650British Heart Foundation PG/12/54/29734British Heart Foundation PG/14/62/31034British Heart Foundation PG/15/39/31519British Heart Foundation PG/17/1/32532British Heart Foundation PG/17/58/33134British Heart Foundation RG/13/4/30107British Heart Foundation RG/19/3/34265Medical Research Council MR/K020919/1NHLBI NIH HHS P01 HL108801NHLBI NIH HHS R01 HL131910NHLBI NIH HHS R01 HL142093NHLBI NIH HHS R01 HL159443NHLBI NIH HHS R42 HL132742Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Lung InjuryAnimalsCase-Control StudiesEndothelial CellsEndotheliumEndotoxemiaFemaleGrowth Differentiation Factor 2HumansMaleMicePulmonary EdemaSepsisGrowth Differentiation Factor 2BMP9BMP signaling in endothelial cellslung injurypulmonary endothelium

Identifiers

PMID33320799
PMCPMC8456542
OpenAlexW3024258509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.