Evidence map›Paper›PMID 33320284›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2022

Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone.

Karlijn J P van Wessem, Luke P H Leenen

Open access · hybridAbstract read
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Influence of Antithrombotics on Severely Injured Patients Over 50 With Blunt Abdominal Trauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Early correction of base deficit decreases late mortality in polytrauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  10. Observational
  11. The effect of age on resilience of health-related quality of life among polytrauma patients: a cross-sectional multicenter study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  12. Role of endocrine PACAP in age-related diseases.Frontiers in endocrinology · 2023
    Review
  13. Article
  14. Multiple Organ Dysfunction in Older Major Trauma Critical Care Patients: A Multicenter Prospective Observational Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karlijn J P van WessemTrauma Surgeon, Department of Trauma Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. kwessem@umcutrecht.nl.ORCID http://orcid.org/0000-0002-1166-0990
Luke P H LeenenProfessor of Trauma Surgery, Department of Trauma Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
University Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAge in severely injured patients has been increasing for decades. Older age is associated with increasing mortality. However, morbidity and mortality could possibly be reduced when accurate and aggressive treatment is provided. This study investigated age-related morbidity and mortality in polytrauma including age-related decisions in initial injury management and withdrawal of life-sustaining therapy (WLST).

methodsA 6.5-year prospective cohort study included consecutive severely injured trauma patients admitted to a Level-1 Trauma Center ICU. Demographics, data on physiology, resuscitation, MODS/ARDS, and infectious complications were prospectively collected. Patients were divided into age subgroups (< 25, 25-49, 50-69, and ≥ 70 years) to make clinically relevant comparisons.

results391 patients (70% males) were included with median ISS of 29 (22-36), 95% sustained blunt injuries. There was no difference in injury severity, resuscitation, urgent surgeries, nor in ventilator days, ICU-LOS, and H-LOS between age groups. Adjusted odds of MODS, ARDS and infectious complications were similar between age groups. 47% of patients ≥ 70 years died, compared to 10-16% in other age groups (P < 0.001). WLST increased with older age, contributing to more than half of deaths ≥ 70 years. TBI was the most common cause of death and decision for treatment withdrawal in all age groups.

conclusionsPatients ≥ 70 years had higher mortality risk even though injury severity and complication rates were similar to other age groups. WLST increased with age with the vast majority due to brain injury. More than half of patients ≥ 70 years survived suggesting geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone.

Indexed as

Multiple TraumaAgedFemaleHumansInjury Severity ScoreIntensive Care UnitsMaleProspective StudiesRetrospective StudiesTrauma CentersAggressive treatmentGeriatric polytraumaWithdrawal of life-sustaining therapy

Identifiers

PMID33320284
PMCPMC7736672
OpenAlexW3112254709

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.