Evidence map›Paper›PMID 33319994›Full record

ReviewEnvironmental science & technology2021

Assessing Human Exposure to SVOCs in Materials, Products, and Articles: A Modular Mechanistic Framework.

Clara M A Eichler, Elaine A Cohen Hubal, Ying Xu, Jianping Cao, Chenyang Bi, Charles J Weschler, Tunga Salthammer, Glenn C Morrison, Antti Joonas Koivisto, Yinping Zhang and 16 more

Abstract readReview
In one paragraph

Review in Environmental science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The impact of particle size on PFAS concentrations in dust from homes in North Carolina and New York and implications for exposure.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2026
    Article
  4. Investigation of Influences on Indoor and Outdoor SVOC Exposure.International journal of environmental research and public health · 2025
    Article
  5. Article
  6. Hydroxyl radical oxidation of chemical contaminants on indoor surfaces and dust.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Modeling Primary Emissions of Chemicals from Liquid Products Applied on Indoor Surfaces.International journal of environmental research and public health · 2022
    Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Clara M A EichlerDepartment of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia 24060, United States.ORCID 0000-0002-1282-3608
Elaine A Cohen HubalOffice of Research and Development, U.S. EPA, Research Triangle Park, North Carolina 27711, United States.
Ying XuDepartment of Building Science, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-1908-7981
Jianping CaoSchool of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou, Guangdong 510006, China.ORCID 0000-0002-8633-388X
Chenyang BiDepartment of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia 24060, United States.ORCID 0000-0003-0131-0310
Charles J WeschlerEnvironmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey 08854, United States.ORCID 0000-0002-9097-5850
Tunga SalthammerFraunhofer WKI, Department of Material Analysis and Indoor Chemistry, Braunschweig 38108, Germany.ORCID 0000-0002-2370-8664
Glenn C MorrisonDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0001-6876-7185
Antti Joonas KoivistoInstitute for Atmospheric and Earth System Research (INAR), University of Helsinki, Helsinki 00014, Finland.
Yinping ZhangDepartment of Building Science, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9175-7890
Corinne MandinUniversity of Paris-Est, Scientific and Technical Center for Building (CSTB), French Indoor Air Quality Observatory (OQAI), Champs sur Marne 77447, France.
Wenjuan WeiUniversity of Paris-Est, Scientific and Technical Center for Building (CSTB), French Indoor Air Quality Observatory (OQAI), Champs sur Marne 77447, France.ORCID 0000-0002-8232-8186
Patrice BlondeauLaboratoire des Sciences de l'Ingénieur pour l'Environnement - LaSIE, Université de La Rochelle, La Rochelle 77447, France.
Dustin PoppendieckEngineering Lab, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States.
Xiaoyu LiuOffice of Research and Development, U.S. EPA, Research Triangle Park, North Carolina 27711, United States.ORCID 0000-0002-8005-7191
Christiaan J E DelmaarNational Institute for Public Health and the Environment, Center for Safety of Substances and Products, Bilthoven 3720, The Netherlands.
Peter FantkeQuantitative Sustainability Assessment, Department of Technology, Management and Economics, Technical University of Denmark, Kgs. Lyngby 2800, Denmark.ORCID 0000-0001-7148-6982
Olivier JollietDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, United States.ORCID 0000-0001-6955-4210
Hyeong-Moo ShinDepartment of Earth and Environmental Sciences, University of Texas at Arlington, Arlington, Texas 76019, United States.ORCID 0000-0002-7001-2555
Miriam L DiamondDepartment of Earth Sciences, University of Toronto, Toronto, Ontario M5S 3B1, Canada.ORCID 0000-0001-6296-6431
Manabu ShiraiwaDepartment of Chemistry, University of California, Irvine, California 92697, United States.ORCID 0000-0003-2532-5373
Andreas ZuendDepartment of Atmospheric and Oceanic Sciences, McGill University, Montreal, Quebec H3A0B9, Canada.ORCID 0000-0003-3101-8521
Philip K HopkeCenter for Air Resources Engineering and Science, Clarkson University, Potsdam, New York 13699-5708, United States.ORCID 0000-0003-2367-9661
Natalie von GoetzFederal Office of Public Health, Berne 3003, Switzerland.ORCID 0000-0001-5257-4573
Markku KulmalaInstitute for Atmospheric and Earth System Research (INAR), University of Helsinki, Helsinki 00014, Finland.
John C LittleDepartment of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia 24060, United States.ORCID 0000-0003-2965-9557

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Intramural EPA EPA999999NIEHS NIH HHS P30 ES001247NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

A critical review of the current state of knowledge of chemical emissions from indoor sources, partitioning among indoor compartments, and the ensuing indoor exposure leads to a proposal for a modular mechanistic framework for predicting human exposure to semivolatile organic compounds (SVOCs). Mechanistically consistent source emission categories include solid, soft, frequent contact, applied, sprayed, and high temperature sources. Environmental compartments are the gas phase, airborne particles, settled dust, indoor surfaces, and clothing. Identified research needs are the development of dynamic emission models for several of the source emission categories and of estimation strategies for critical model parameters. The modular structure of the framework facilitates subsequent inclusion of new knowledge, other chemical classes of indoor pollutants, and additional mechanistic processes relevant to human exposure indoors. The framework may serve as the foundation for developing an open-source community model to better support collaborative research and improve access for application by stakeholders. Combining exposure estimates derived using this framework with toxicity data for different end points and toxicokinetic mechanisms will accelerate chemical risk prioritization, advance effective chemical management decisions, and protect public health.

Indexed as

Air PollutantsAir Pollution, IndoorVolatile Organic CompoundsDustHumansOrganic ChemicalsAir PollutantsDustOrganic ChemicalsVolatile Organic Compounds

Identifiers

PMID33319994
PMCPMC7877794

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.