Evidence map›Paper›PMID 33319610›Full record

Observational studyJournal of the renin-angiotensin-aldosterone system : JRAAS

Impact of contrast-induced acute kidney injury on the association between renin-angiotensin system inhibitors and long-term mortality in heart failure patients.

Li Lei, Yulu Huang, Zhaodong Guo, Feier Song, Yibo He, Jin Liu, Guoli Sun, Bowen Liu, Pengyuan Chen, Jianbin Zhao and 9 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of the renin-angiotensin-aldosterone system : JRAAS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Li LeiThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-5429-9675
Yulu HuangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Zhaodong GuoDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated with South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Feier SongDepartment of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Yibo HeDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated with South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Jin LiuDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated with South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Guoli SunDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated with South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Bowen LiuGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Pengyuan ChenDepartment of Cardiology, Guangdong General Hospital's Nanhai Hospital, The Second Hospital of Nanhai District Foshan City, Foshan, China.
Jianbin ZhaoDepartment of Cardiology, Jiangmen Central Hospital, Jiangmen, Guangdong, China.
Dengxuan WuDepartment of Cardiology, Panzhihua Central Hospital, Panzhihua, China.
Yan XueDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Wenhe YanDepartment of Cardiology, Maoming People's Hospital, Maoming, Guangdong, China.
Zefeng LinDepartment of Neurology, Maoming People's Hospital, Maoming, Guangdong, China.
Xiuqiong HuangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Guanzhong ChenGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Shiqun ChenDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated with South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Yong LiuThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Jiyan ChenThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRenin-angiotensin system inhibitors (RASi) reduce mortality among heart failure (HF) patients, but their effect among those complicating contrast-induced acute kidney injury (CI-AKI) remains unexplored. We aimed to investigate whether the relationship between RASi prescription at discharge and mortality differs between HF patients with or without CI-AKI following coronary angiography (CAG).

methodsAbout 596 HF patients from an observational cohort were divided into a CI-AKI group (

resultsDuring the median follow-up time of 2.26 (1.70; 3.24) years, higher mortality rate was observed in the CI-AKI group compared to the non-CI-AKI group (18.3% vs 8.9%,

conclusionRASi prescription at discharge for HF patients complicating CI-AKI tended to be ineffective, while it benefited those without CI-AKI. Further randomized evidence is needed to confirm this trend.

Indexed as

Renin-Angiotensin SystemAcute Kidney InjuryAgedContrast MediaFemaleHeart FailureHospital MortalityHumansMaleMiddle AgedMultivariate AnalysisPrescription DrugsRisk FactorsContrast MediaPrescription Drugsangiotensin-converting enzymes inhibitorsangiotensin-receptor blockerscontrast-induced acute kidney injuryheart failuremortalityRenin-angiotensin system inhibitors

Identifiers

PMID33319610
PMCPMC7745565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.