Evidence map›Paper›PMID 33319606›Full record

ArticleApplied spectroscopy2021

Predicting the Refractive Index of Tissue Models Using Light Scattering Spectroscopy.

Michelle Bailey, Benjamin Gardner, Martina Alunni-Cardinali, Silvia Caponi, Daniele Fioretto, Nick Stone, Francesca Palombo

Abstract read
In one paragraph

Article in Applied spectroscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michelle BaileySchool of Physics and Astronomy, University of Exeter, Exeter, UK.
Benjamin GardnerSchool of Physics and Astronomy, University of Exeter, Exeter, UK.
Martina Alunni-CardinaliDepartment of Physics and Geology, University of Perugia, Perugia, Italy.
Silvia CaponiCNR-IOM - Istituto Officina dei Materiali - Research Unit in Perugia, c/o Department of Physics and Geology, University of Perugia, Perugia, Italy.
Daniele FiorettoDepartment of Physics and Geology, University of Perugia, Perugia, Italy.
Nick StoneSchool of Physics and Astronomy, University of Exeter, Exeter, UK.
Francesca PalomboSchool of Physics and Astronomy, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0001-6355-2601

Funding

Cancer Research UK 24341
6 · The paper itself

Abstract

In this work, we report the application of Raman microspectroscopy for analysis of the refractive index of a range of tissue phantoms. Using both a custom-developed setup with visible laser source and a commercial microspectrometer with near infrared laser, we measured the Raman spectra of gelatin hydrogels at various concentrations. By building a calibration curve from measured refractometry data and Raman scattering intensity for different vibrational modes of the hydrogel, we were able to predict the refractive indices of the gels from their Raman spectra. This work highlights the importance of a correlative approach through Brillouin-Raman microspectroscopy for the mechano-chemical analysis of biologically relevant samples.

Indexed as

RefractometrySpectrum Analysis, RamanHydrogelsLightVibrationHydrogelsbiomechanicsBiopolymersBrillouin microscopyRaman scatteringvibrational spectroscopy

Identifiers

PMID33319606
PMCPMC8114435

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.