Evidence map›Paper›PMID 33319559›Full record

ArticleAnalytical chemistry2021

Assessment of the Maximal Activity of Complex IV in the Inner Mitochondrial Membrane by Tandem Electrochemistry and Respirometry.

Nathan L Frantz, Gabrielle Brakoniecki, Dawei Chen, Denis A Proshlyakov

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. The electron transport chain ofApplied and environmental microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nathan L FrantzDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322, United States.ORCID 0000-0003-4726-2385
Gabrielle BrakonieckiDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322, United States.
Dawei ChenDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322, United States.
Denis A ProshlyakovDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322, United States.ORCID 0000-0003-4625-0323
Michigan State University · US

Funding

Ceramide-mediated mitochondrial damage in diabetic retinopathy investigated by novel microfluidic O2 sensing and bio-mimetic electrochemistryR01EY028049 · NEI · MICHIGAN STATE UNIVERSITY · PI BUSIK, JULIA V, PROSHLYAKOV, DENIS A · 2018 to 2021
$1.5M
NEI NIH HHS R01 EY028049
6 · The paper itself

Abstract

Assessment of activities of mitochondrial electron transport enzymes is important for understanding mechanisms of metabolic diseases, but structural organization of mitochondria and low sample availability pose distinctive challenges for in situ functional studies. We report the development of a tandem microfluidic respirometer that simultaneously tracks both the reduction of mediators on the electrode and the ensuing reduction of O

Indexed as

Electrochemical TechniquesMicrofluidic Analytical TechniquesAnimalsElectron TransportElectron Transport Complex IVMitochondria, HeartMitochondrial MembranesOxygenRabbitsElectron Transport Complex IVOxygen

Identifiers

PMID33319559
PMCPMC8772154
OpenAlexW3113184929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.