ArticleJournal of veterinary internal medicine2021
Serum 25-hydroxyvitamin D concentration and infectious respiratory disease complex in shelter dogs.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Correlation between 25-hydroxyvitamin D, N-terminal pro-brain natriuretic peptide, inflammatory factors and myocardial injury in children with mycoplasma pneumoniae pneumonia.BMC pediatrics · 2025Article
- Diagnostic Utility of Canine C-Reactive Protein, Haptoglobin, and 25-Hydroxyvitamin-D in Dogs with Nasal Cavity Disease.Animals : an open access journal from MDPI · 2024Article
- Evaluation of serum 25-hydroxyvitamin D, C-reactive protein, and haptoglobin as biomarkers in dogs newly diagnosed with histoplasmosis.Journal of veterinary internal medicine · 2023Article
- Serum 25-hydroxyvitamin D concentrations in dogs with coccidioidomycosis and variables associated with extent of clinically evident disease.Journal of veterinary internal medicine · 2023Article
- Relationship between Acute Respiratory Tract Infection and the Serum 25(OH) D3 Level in Chronic Kidney Disease Patients and Its Prevention and Treatment.BioMed research international · 2022Article
- Serum 25-hydroxyvitamin D concentration and infectious respiratory disease complex in shelter dogs.Journal of veterinary internal medicine · 2021Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypovitaminosis D is a risk factor for the development of respiratory infections in humans and repletion can be protective.
objectivesDetermine if serum 25-hydroxyvitamin (OH)D concentrations are lower in shelter dogs and if 25(OH)D concentrations are associated with clinical signs of canine infectious respiratory disease complex (CIRDC) or with time in the shelter. ANIMALS: One hundred forty-six shelter dogs (clinically ill n = 36, apparently healthy n = 110) and 23 nonshelter control dogs.
methodsProspective cohort study. Shelter dogs were grouped as clinically ill or apparently healthy based on the presence or absence, respectively, of clinical signs associated with CIRDC. Serum 25(OH)D concentrations were measured with a competitive chemiluminesence immunoassay. Nucleic acids of agents associated with the CIRDC were amplified by polymerase chain reaction assays.
resultsThe concentration of 25(OH)D was 7.3 ng/mL (4.5-9.9, 95% confidence interval [CI]) lower in dogs with signs of CIRDC than apparently healthy shelter dogs (t(142) = 2.0, P = .04). Dogs positive for DNA of canine herpesvirus (CHV)-1 had serum 25(OH)D concentrations 14.9 ng/mL (-3.7 to 29.6, 95% CI) lower than dogs that were negative (t(137) = 2.0, P = .04). Serum 25(OH)D concentrations in shelter dogs were not different from control dogs (t(45) = -1.4, P = .17). Serum 25(OH)D concentration was not associated with duration of time in the shelter (F(1, 140) = 1.7, P = .2, R CONCLUSION AND CLINICAL IMPORTANCE: Vitamin D could have a role in acute respiratory tract infections in shelter dogs.
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